Disadvantages Of Tablets Compared To Capsules
The two most common oral solid dosage forms are capsules and tablets. While the focus of this article is on capsules for liquid filling, it is useful to know the tablet formulation as a point of comparison.
While tablets are the most common oral solid dosage form, tablets do have some disadvantages:
The tablet is only a compressed medication, so it may taste bitter or unpleasant for patients who have difficulty swallowing the tablet. Tablets may also have an odor that may be objectionable to some consumers. This can be overcome with coatings, although adding coatings increases manufacturing costs.
Related to the last point, uncoated tablets are more likely to irritate the esophagus after swallowing.
Tablets dissolve more slowly than capsules, which means they take longer to start working.
Capsules are more suitable for sustained release and targeted drug delivery.
Tablets are less bioavailable than capsules because they may not break down completely.
Capsules are easier to formulate, which means shorter development and manufacturing times.
Consumers prefer capsules to tablets. Pharmaceutical companies are even reformulating existing tablet formulations into capsules to meet consumer demand.
Tablets are easier to tamper with because they can be crushed and split. Also, capsules are harder to counterfeit than tablets.
Hexin Capsule Co., Ltd. is an Empty Pharmaceutical Capsules Manufacturer from China, producing and selling Clear Vegetarian Capsules such as Empty HPMC Capsules.
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