The recombinant therapeutic antibodies and proteins market comprises various antibody and peptide-based drugs that are produced through recombinant DNA technology. These biologics are widely used for treating conditions such as cancer, autoimmune diseases, and other chronic ailments. The market has witnessed significant growth over the past few years owing to rising prevalence of various chronic and lifestyle-related diseases globally.

The global recombinant therapeutic antibodies and proteins market is estimated to be valued at US$ 150 Bn in 2023 and is expected to exhibit a CAGR of 7% over the forecast period 2023-2028, as highlighted in a new report published by Coherent Market Insights.

Market Dynamics
The recombinant therapeutic antibodies and proteins market is witnessing strong growth due to increasing prevalence of chronic diseases (one driver from heading). Chronic diseases such as cancer, diabetes, cardiovascular diseases are majorly driven by change in lifestyle patterns like physical inactivity, tobacco use and consumption of unhealthy diets. According to the World Health Organization (WHO), chronic diseases cause 71% of all deaths globally with approximately 63% of total deaths in the United States. Growing prevalence of such chronic diseases will significantly drive the demand for advanced treatment options like recombinant therapeutic antibodies and proteins over the forecast period.

The second major driver of recombinant therapeutic antibodies and proteins market is rapid technological advancements. Continuous developments in recombinant DNA technology have enabled large-scale production of antibodies and proteins with high efficiency and in more complex structure compared to conventional drugs, thereby increasing efficacy and reducing side effects of treatment. This has gradually increased the acceptance of biologics over traditional therapeutic options. Growing investments in research and development of novel and advanced antibody drug formulations will further support market growth over the next few years.

SWOT Analysis
Strength: Recombinant therapeutic antibodies and proteins have revolutionized medicine for treatment of various diseases. They have high specificity and affinity for target antigens with minimal side effects. Production using mammalian cell culture systems allows for human-like post-translational modifications critical for biological activity and efficacy.

Weakness: Recombinant therapeutics are complex molecules requiring highly specialized purification techniques which adds to manufacturing costs. Challenges exist in achieving consistent quality attributes during large-scale production. Biosimilars have narrow therapeutic indices which require rigorous assessment of safety and efficacy.

Opportunity: Biologics have potential for treatment of several chronic and genetic disorders that were previously untreatable. Personalized medicine using companion diagnostics may expand the target patient population for biologics. Emerging technologies such as continuous manufacturing can boost production capacities and reduce costs.

Threats: Patent cliffs of many blockbuster antibodies will drive increased competition from biosimilars. Stringent regulations exist for biosimilar approval which adds to development timelines and costs. Supply chain disruptions due to pandemic had impacted production capacities in the past.

Key Takeaways
Global Recombinant Therapeutic Antibodies And Proteins Market is expected to witness high growth. Monoclonal antibodies dominate application segment owing to approvals for oncology and immunology indications.

Regional analysis: North America accounts for the largest share due to approvals of novel biologics and expanding target patient population in the US. In Europe, Germany, the UK and France contribute significantly to the regional market. China is the leading market in Asia Pacific supported by government initiatives to strengthen biosimilar development capabilities. Rising accessibility to healthcare services across countries like India, Japan and South Korea is propelling growth in Asia Pacific.

Key players: Key players operating in the recombinant therapeutic antibodies and proteins market are Amgen, Abbott Laboratories, F. Hoffmann-La Roche Ltd, Johnson & Johnson, Merck & Co., Inc., Pfizer Inc., Eli Lilly and Company, Bristol-Myers Squibb Company, Novartis AG and Sanofi.

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