Q-TOF Mass Spectrometer is a powerful analytical technique used in mass spectrometry. It is often compared to other mass spectrometry techniques such as triple quadrupole (QQQ) and Orbitrap mass spectrometry. Q-TOF Mass Spectrometer is unique in that it combines the separation capabilities of a quadrupole ion guide with the high-resolution and accurate mass measurements of a time-of-flight (TOF) analyzer. This allows for high-resolution, accurate mass measurements of analytes in complex matrices.
Compared to triple quadrupole mass spectrometry, Q-TOF Mass Spectrometer has a higher resolution and sensitivity, making it ideal for the identification and characterization of complex molecules. However, QQQ has higher selectivity and is more suitable for quantification purposes. Orbitrap mass spectrometry, on the other hand, has higher resolution and mass accuracy than Q-TOF Mass Spectrometer but has a lower sensitivity. The choice of mass spectrometry technique depends on the analytical needs and the nature of the sample.
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https://cmitoc.blogspot.com/2023/04/q-tof-mass-spectrometer-help-identify.html
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