The most accessible and affordable chemical structure found in nature is often the source of synthetic Vanillin. Historically, the building block of choice was lignin, a by-product of the paper industry.

 The benzene group and the two oxygen groups are shared, as can be seen in the structure of lignin below. For the distinctive aldehyde group to be added, just one reaction is required. Today, synthetic Vanillin is also produced using guaiacol. There is a brand-new Vanillin on the market that is marketed as natural. This Vanillin is produced by a biosynthetic process that involves the fermentation of sugar or rice derivatives.

 Because fermentation is used to convert the substrate into Vanillin, it is referred to as natural Vanillin.  It costs around ten times as much to produce Vanillin this way as it does to produce it synthetically, and only a handful of businesses utilise this process.

Read More - https://latesthighlightscmi.blogspot.com/2023/04/in-vast-majority-of-synthetic-vanillin.html