Single-layer Seam Sealing Tapes can only be heat welded to polyurethane coated materials. For example, waterproof coats employ a two-layer seam sealing tape to stop water from seeping between stitch seams. Seam sealing tape is used during construction to close any gaps or breaches that could let moisture or air into the building envelope. To make sure that no outside elements enter the structure, it is typically employed around the edges of an air or vapour barrier.

The area around door frames, windows, and corners can also benefit from additional air and moisture protection with this technique. Personal Protective Equipment (PPE) suits employ Seam Sealing Tapes, also known as PPE tape or seam tape, to completely seal off the seams created during the stitching process, protecting the suit against bacterial and viral contamination. To seal the seam and keep water and air out, use a three-layer seam sealing tape.

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