Prothrombin Complex Concentrates (PCC) are a type of medication used in the management of bleeding disorders, particularly those caused by deficiencies in blood clotting factors.

Prothrombin Complex Concentrates are made from human plasma and contain a combination of clotting factors, including factors II, VII, IX, and X, as well as proteins C and S. PCCs work by increasing the levels of these clotting factors in the blood, which helps to form a clot and stop bleeding.

Prothrombin Complex Concentrates are available in several different formulations, including 3-factor, 4-factor, and activated PCCs. The choice of formulation depends on the specific needs of the patient and the severity of their bleeding disorder. PCCs are typically administered intravenously and are most effective when given as early as possible in the course of bleeding.