Ammonium thioglycolate is an organic compound with the formula HSCH2CO2NH4, which can be used as a cold pressing solution.

Ammonium thioglycolate is a colorless liquid with a sulfur odor. Molecular weight 92.12. The relative density is 1.3253. Melting point -16.5℃. Boiling point 123℃(3.866×103Pa), 120℃(2.666×103Pa), 108℃(2.000×103Pa), 96℃(0.667×103Pa), 79.5℃(1.333×103Pa), flash point 128℃. Refractive index 1.5030. Insoluble in petroleum ether, miscible with water, ethanol, methanol, acetone, ether, chloroform and benzene. It oxidizes rapidly in air. A small amount of iron, copper, manganese ions exist, can accelerate oxidation.

preparation

Ammonium thioglycolate can be prepared with sodium chloroacetate and thiourea as raw materials:

ClCH2COONa + H2NC(S)NH2 —80℃→ HN=C(NH2)S-CH2COOH + NaCl

2 HN=C(NH2)S−CH2COOH + Ba(OH)2 → Ba(SCH2COO)2Ba + 2 NH2CONH2 + H2O

Ba(SCH2COO)2Ba + 2 NH4HCO3 → 2HSCH2COONH4 + 2 BaCO3

use

Ammonium thioglycolate structure contains sulfhydryl and carboxylic groups, can be used as antioxidants, catalysts, etc., in the field of chemistry has a wide range of applications. 

Ammonium thioglycolate is a daily chemical raw material developed in the 1940s, which is used as a hair removal agent and curling agent in functional cosmetics. At present, thioglycolate and its salts (calcium salt, ammonium salt) are used in cosmetics, and calcium thioglycolate is mostly used in hair removal products.