Sodium phenylbutyrate is a four-carbon aromatic acid derivative that is a prodrug of phenylbutyrate. It is used as an ammonia scavenger for various urea cycle disorder treatments and has applications in various industries like food additive, fragrance ingredient, pharmaceutical intermediate etc. Sodium phenylbutyrate helps in removal of nitrogen from the blood in the form of harmless substances, preventing toxic build up of ammonia in blood which can otherwise cause neurological damage and death.
The global sodium phenylbutyrate market is estimated to be valued at US$ 1.92 Bn in 2023 and is expected to exhibit a CAGR of 4.2% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.
Market Dynamics:
The increasing applications of sodium phenylbutyrate in various industries owing to its properties like ammonia scavenging is estimated to drive the market growth over the forecast period. Sodium phenylbutyrate is majorly used in pharmaceutical industry for treatment of various urea cycle disorders like hepatic encephalopathy and as an adjuvant therapy for lysosomal storage disorders. It removes excess nitrogen by enabling ornithine to bind with phenylacetylglutamine preventing further accumulation of ammonia thus rescuing patients during hyperammonemic crisis. Additionally, sodium phenylbutyrate also finds applications as food additive and fragrance ingredient in food and cosmetic industry due to its aromatic properties. Growing food processing industry and personal care industry is thus also expected to boost the market growth of sodium phenylbutyrate over the forecast period.
SWOT Analysis
Strength: Sodium phenylbutyrate has a long history of use for the treatment of urea cycle disorders. It is included in the WHO's list of essential medicines. Research has also found it may help reduce pressure on the heart. Moreover, growing awareness about its therapeutic applications will drive market demand.
Weakness: Side effects such as nausea, vomiting, abdominal pain and diarrhea limit its use in some patients. High cost also restricts widespread adoption. Limited research into new therapeutic areas also constrains market growth potential.
Opportunity: Expanding into new therapeutic areas offers significant opportunities. Research into its potential treatment applications for neurological diseases and cancers show promise. Emerging economies with large patient populations represent new markets. Growing healthcare budgets can boost access in developing nations.
Threats: Stiff competition from alternative drug therapies poses a major threat. Generic competition erodes brand loyalty and price margins. Stringent regulatory norms and lengthy approval times also impact market viability of new products.
Key Takeaways
The Global Sodium Phenylbutyrate Market Demand is expected to witness high growth over the forecast period.
Regional analysis comprises: North America currently dominates driven by growing incidence of urea cycle disorders and rising healthcare spending. The region holds over 40% market share. Asia Pacific is anticipated to grow at the fastest pace due to rising healthcare infrastructure, increasing diagnosis rates, and growing medical tourism.
Key players operating in the sodium phenylbutyrate market are Procter & Gamble (P&G) Chemicals, CREMER, Wilmar, VVF Ltd., KLK OLEO, Inoue Perfumery MFG, Wuhan Yuancheng Gongchuang, Changsha Jianglong Chemicals, Godrej Industries. These companies are focusing on new product approvals and launches to strengthen their market position.
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