Smallpox is a deadly infectious disease caused by the variola virus. Throughout history, it has afflicted humanity with devastating consequences. Considered one of the most fatal illnesses known to humans, smallpox has wiped out entire villages and populations. However, advances in science and medicine have led to the development of vaccines and treatments that have eradicated this disease. This article discusses the history of smallpox treatment from ancient times to modern vaccination techniques that have eliminated smallpox worldwide.

Early Methods
The earliest recorded techniques for smallpox treatment date back to ancient China and India thousands of years ago. Smallpox Treatment Physicians in these civilizations practiced crude forms of variolation where material from smallpox lesions was introduced into the skin of healthy individuals to induce a mild form of the disease and confer immunity. This practice slowly spread to other parts of Asia, Africa, the Middle East and Europe.

In the 1700s, variolation became more organized in countries like England where lay variolators performed the technique despite its risks. The development of inoculation involved making a tiny cut and rubbing infected material into the wound instead of direct injection. This reduced the risk of contracting full-blown smallpox but still spread the virus. Though risky, these early methods provided some protection before the advent of vaccination.

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