Protein engineering is a field of biotechnology that involves the design and development of modified proteins for therapeutic and industrial applications. Protein engineering is based on the principles of protein structure and function, and involves the use of genetic engineering, protein chemistry and computational modeling to create proteins with desired properties.
The goal of protein engineering is to create proteins with specific functions, such as increased stability, increased solubility, increased target binding affinity or improved enzymatic activity. For example, protein engineering can be used to design specific enzymes for industrial processes, antibodies for targeted drug delivery or engineered peptides for targeted therapies.
Protein engineering has a wide range of applications in biotechnology, medicine and industrial processes. In biotechnology, protein engineering can be used to create more efficient bioprocessing enzymes, such as proteases, amylases and lipases. In medicine, protein engineering can be used to create protein-based pharmaceuticals, such as monoclonal antibodies, insulin and growth hormones.
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In industrial processes, protein engineering can be used to create enzymes for bioremediation, biofuels production and food processing. Protein engineering is a complex process that requires a multidisciplinary approach. The process involves the identification of relevant proteins, the design of modified proteins, the synthesis of engineered proteins, the analysis of protein structure and function, and the testing of engineered proteins in relevant systems.
Based on product & service, the market is segmented into instruments, consumables, and software & services. Instruments formed the largest product segment in this market owing to technological advancements and the high price of mass spectroscopy and crystallography instruments (as compared to consumables).
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North America was the largest regional market for protein engineering products and services in 2019
In 2019, North America accounted for the largest share of the global market, followed by Europe. The large share of the North American market is attributed to the presence of well-established CROs, rising R&D expenditure, and the availability of the latest techniques and instruments for drug discovery research in the region. Also, the rising adoption of biologic drugs such as monoclonal antibodies, erythropoietin, and interferons for the treatment of chronic diseases is a major factor driving the growth of the North American market.
The major companies operating in the global Protein Engineering Market include Thermo Fisher Scientific (US), Danaher Corporation (US), Agilent Technologies (US), and Bio-Rad Laboratories (US).
Research Developments :
· In 2019, Creative Biolabs (US) launched the cd25 monoclonal antibody.
· In 2019, Waters Corporation (US) launched Vanguard FIT Cartridge Technology.
· In 2019, Agilent Technologies (US) acquired BioTek Instruments (US), which helped the company to expand its expertise in cell analysis and establish its position in the immuno-oncology and immunotherapy markets.
· In 2019, Merck KGaA signed a license agreement with Amunix Pharmaceuticals, Inc. (US). Under this agreement, Amunix will gain the rights to develop therapeutics using the protease-triggered immune activator (ProTIA) technology platform.
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