The global plasma fractionation market size was valued at USD 26,842.9 million in 2021 and is poised to grow at a significant CAGR of 6.8% during the forecast period 2022-28.  Plasma fractionation refers to the process of separation, extraction, and purification of plasma. Human plasma contains the large variety of proteins, however, only a few of these proteins are help in producing therapeutic plasma products. Plasma is used in prevention and treatment of various life-threatening diseases caused by trauma, immunologic disorders, and infections. The plasma fractionation process is majorly used in treating protein deficiency condition in healthcare applications. The proteins extracted from the plasma are majorly categorized into three main classes: immunoglobulins which are useful in the treatment of autoimmune disorders and increasing the immune response of the body, clotting factors which are help in treatment of blood disorders such as haemophilia, and the albumins which are useful in conditions of decreased albumin levels or during fluid loss. Plasma fractionation process is carried by different criteria such as solubility of the products, and their physical and chemical conditions such as ionic strengths, pH levels, and temperature, etc.

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Plasma fractionation market expected to grow at significant rate over the forecast period due to rise in the incidence of immune and bleeding disorders, increase in the use of alpha-1 antitrypsin and immunoglobulin, rise in prevalence of Alpha-1 Antitrypsin Deficiency (AATD), emphysema, and haemophilia. In addition, development in plasma techniques and plasma utilization are the key factors expected to boost the plasma fractionation market. However, high cost for the plasma products, adverse effects associated with the plasma fractionation products, lack of reimbursement policies, stringent regulatory policies, and increase in the recombinant coagulation factors might hinder the growth of plasma fractionation market over the forecast timeframe.

The global plasma fractionation market segmentation:

  • By Product Type: Albumin, Immunoglobulin, Coagulation Factor Concentrates, Protease Inhibitors and Other Plasma Fractionation Products
  • By Application: Neurology, Haematology, Immunology, Rheumatology, Haemato-oncology, Critical Care, Pulmonology and Others
  • By End Users: Hospitals, Clinics, Academic Institutes and Clinical Research Laboratories

 

Geographically, global plasma fractionation market has been segmented into following regions Viz. North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. North America dominates the global plasma fractionation market followed by Europe and Asia-Pacific. Europe is the second largest region for global plasma fractionation market due to the rise in aging population and increase in the prevalence of chronic diseases.

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Some of the major players working in plasma fractionation market, which include Grifols S.A (Spain), CSL Ltd. (Australia), Shire (Ireland, Octapharma AG (Switzerland), Kedrion S.p.A (Italy), China Biologic Products, Inc. (China), Biotest AG (OGEL GmbH) (Germany), LFB S.A (France), Sanquin (Netherlands)



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