What are Antisense Oligonucleotides?Antisense oligonucleotides (ASOs) are short engineered nucleic acid sequences designed to specifically bind to target messenger RNA (mRNA) molecules and interfere or "silence" gene expression. ASOs are generally 15-25 nucleotides in length and are chemically modified to increase their stability and binding affinity for mRNA. By binding to mRNA, ASOs can block...
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