Glycine use and ingestion can have a number of negative side effects, including nausea, sleepiness, vomiting, stomach distress, and diarrhoea. The use of glycine in products like animal feeds, food and beverage items, dietary supplements, and others is being discouraged as a result, which is limiting the global Glycine Market ability to grow.  In addition, the market for glycine is being hampered by the availability of substitutes like arginine and other solubilizing, emulsifying, and sweetening agents in the food and beverage and cosmetics industries.

The prevalence of metabolic syndrome and sleep issues is rapidly increasing, which is feeding the demand for related therapy and pharmaceuticals. This is due to the increased adoption of various lifestyles and changing dietary habits. For instance, the American Sleep Association estimates that between 50 and 70 million Americans suffer from sleep problems, with 25 million of these individuals having obstructive sleep apnea. The prevalence of sleep disorders is anticipated to increase demand in the global Glycine Market because glycine is widely employed in the formulation of medications for the aforementioned ailments.

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