What is Vigabatrin Sachet?
Vigabatrin sachet is a prescription medication used to treat specific types of seizures, particularly infantile spasms and refractory complex partial seizures. It is a form of vigabatrin, an antiepileptic drug that works by increasing the amount of gamma-aminobutyric acid (GABA) in the brain, which helps to reduce abnormal nerve activity.
How Vigabatrin Sachet Works
Vigabatrin sachet contains the active ingredient vigabatrin, which inhibits the enzyme GABA transaminase. This enzyme normally breaks down GABA, a neurotransmitter that calms nerve activity in the brain. By blocking this enzyme, vigabatrin increases GABA levels, helping to stabilize brain function and reduce seizures.
Medical Uses of Vigabatrin Sachet
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Infantile Spasms (IS): A rare epilepsy syndrome in infants, treated effectively with vigabatrin as a first-line therapy.
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Refractory Complex Partial Seizures: For patients not responding well to other antiepileptic medications, vigabatrin can be added as an adjunct therapy.
How to Take Vigabatrin Sachet
Dosage and Administration
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Vigabatrin sachet is usually mixed with water and taken orally.
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The dosage depends on the patient's age, weight, and medical condition.
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It is important to follow the prescribed dosing schedule without skipping or doubling doses.
Mixing Instructions
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Open the sachet and pour the powder into a cup.
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Add the specified amount of water (usually 10 mL per sachet).
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Stir well until the powder dissolves completely.
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Administer the full mixture immediately.
Important Safety Information
Possible Side Effects
Warnings and Precautions
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Eye Exams: Regular eye tests are mandatory during treatment, as vigabatrin can cause serious vision problems.
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Pregnancy: Vigabatrin should only be used in pregnancy if absolutely necessary.
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Withdrawal: Never stop using vigabatrin suddenly, as this may trigger seizures.
Storage and Handling
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Store sachets at room temperature in a dry place.
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Keep out of reach of children.
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Do not use expired sachets.
Conclusion
Vigabatrin sachet is a valuable medication for managing difficult-to-treat seizures, particularly in infants and individuals with complex epilepsy. However, it must be used carefully and under strict medical supervision due to potential side effects, especially related to vision. Always follow your healthcare provider’s instructions and attend regular check-ups to ensure safe use.
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