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Understanding Corticosteroid Therapy in Duchenne Muscular Dystrophy (DMD) Treatment

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Corticosteroid therapy is a cornerstone of Duchenne Muscular Dystrophy (DMD) treatment. These medications, such as prednisone and deflazacort, have shown significant benefits in slowing disease progression and prolonging ambulation in individuals with DMD. Corticosteroids work by reducing inflammation and suppressing muscle fiber damage, thus preserving muscle strength and function. However, it's important to note that corticosteroid therapy is not without potential side effects. Common adverse effects include weight gain, osteoporosis, cataracts, and behavioral changes. Regular monitoring and management of these side effects are necessary to minimize their impact. Healthcare providers closely monitor growth, bone health, and psychological well-being while balancing the benefits and risks of corticosteroid therapy. Understanding the nuances of corticosteroid treatment is crucial in providing comprehensive care to individuals with DMD and making informed decisions about the most suitable treatment approach.

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