Pressure was put on Inarius to wipe them out, though he was unable to destroy his own children D2R ladder items. Instead, Inarius re-tuned the Worldstone to cause nephalim powers to diminish over time and that any use of powers in his world would be punished. Lilith began turning on her followers over the prospect of her children being killed off.
Where are they now?
Following the carnage brought on by Lilith, Inarius captured and ultimately banished her into an endless realm called the Void, unable to kill her himself. While she eventually escaped during the Sin War, she was eventually defeated and sent back. She remained stuck in the Void for thousands of years until she was eventually summoned back into Sanctuary by a member of the Triune, followers of the Prime Evils.
Inarius eventually disappeared from the public eye, choosing to walk among humanity and manipulate events from behind the scenes. Eventually, the Burning Hells had discovered the existence of Sanctuary, invading the once prosperous and peaceful world.
A new generation of nephalem led by Uldyssian also rebelled against both factions which would also cause the High Heavens to get involved in the conflict. As the fighting raged on, Uldyssian not only helped bring down Lilith but altered the Worldstone to destroy the bond Inarius had with it. Ultimately impressed by the nephalem cheap diablo 2 resurrected items, the Angiris Council agreed to spare Sanctuary and the people living there.