Florence, Italy is a city rich in history, art, and culture. There are numerous things to see and do in Florence that cater to a wide range of interests. Here are some must-visit places and activities:

1. Uffizi Gallery: This world-renowned art museum houses an incredible collection of Renaissance masterpieces, including works by Michelangelo, Leonardo da Vinci, Botticelli, and more.

2. Galleria dell'Accademia: Home to Michelangelo's famous sculpture "David," this museum also features other impressive artworks and sculptures.

3. Florence Cathedral (Duomo): Climb to the top of the Duomo's dome for panoramic views of the city. Also, explore the Baptistery and Giotto's Campanile nearby.

4. Ponte Vecchio: This medieval bridge is lined with shops selling jewelry, art, and souvenirs. It's a beautiful spot for a leisurely stroll and offers picturesque views of the Arno River.

5. Palazzo Vecchio: This historic palace is a symbol of Florence's political power and features impressive rooms and chambers open to the public.

6. Boboli Gardens: Located behind the Pitti Palace, these gardens offer a peaceful escape with stunning sculptures, fountains, and greenery.

7. Santa Maria Novella: This basilica showcases magnificent Gothic and Renaissance architecture, as well as impressive frescoes and art.

8. Mercato Centrale: A bustling indoor market where you can sample and buy a variety of Italian foods, wines, and gourmet products.

9. Oltrarno District: Cross the Ponte Vecchio to explore this charming area known for its artisan workshops, local cafes, and vibrant atmosphere.

10. Piazzale Michelangelo: Head here for breathtaking panoramic views of Florence, especially during sunset.

11. Florence Leather Market: If you're interested in shopping, the San Lorenzo Market and surrounding area is famous for its leather goods, clothing, and souvenirs.

12. Climb the Campanile: Giotto's Campanile is a separate bell tower near the Duomo that offers another great vantage point to see the city.

13. Museo Galileo: If you're interested in science and astronomy, this museum showcases a vast collection of scientific instruments and artifacts.

14. Visit the Palazzo Pitti: This grand palace hosts various museums and galleries, including the Palatine Gallery and the Royal Apartments.

15. Enjoy Tuscan Cuisine: Indulge in traditional Tuscan dishes at local restaurants. Don't miss out on the Florentine steak (bistecca alla fiorentina) and classic Italian gelato.

Remember that Florence can be quite busy with tourists, especially during peak seasons. It's a good idea to book tickets in advance for popular attractions to save time and avoid long lines. Exploring the city on foot is a wonderful way to soak in its beauty and discover hidden gems along the narrow streets and charming squares.