Acellular dermal matrices are sheets of human dermal tissue that are acellular and collagen-based biologic products used to reinforce and support soft tissue repairs or to replace damaged or inadequate integumental tissue. They are commonly used for facial and abdominal wall reconstruction and breast reconstruction surgeries.
The global acellular dermal matrices market is estimated to be valued at US$ 2783.32 Mn in 2023 and is expected to exhibit a CAGR of 5.5% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.
Market Dynamics
The U.S. acellular dermal matrices market is expected to witness significant growth over the forecast period, owing to rising adoption in surgical procedures. According to American Society of Plastic Surgeons, there were around 324,000 breast reconstruction surgeries performed in 2020 in the U.S. With growing breast cancer prevalence in the country, the demand for acellular dermal matrices for breast reconstructions is expected to increase significantly. Acellular dermal matrices act as scaffolds to support and integrate with host tissue, allowing three-dimensional volume in breast reconstructions. Moreover, rising number of facial reconstruction procedures for trauma injuries and defects such as cleft lips and cleft palates are also likely to propel the market growth. For instance, it is estimated that around 7,500 new cleft cases are diagnosed annually in the U.S.
SWOT Analysis
Strength: Acellular dermal matrices offer a suitable alternative when conventional wound dressings are not able to support or correct wound healing. They act as a scaffold that facilitates tissue regeneration and help close wounds through tissue ingrowth. They also do not cause an immune response or rejection. Multiple clinical data and studies have proven their effectiveness and safety for wound healing applications.
Weakness: Acellular dermal matrices are derived from cadaveric or animal tissues and carry a small risk of disease transmission or rejection by the patient's immune system. Their production processes may not completely remove all non-cellular components and cellular debris from the tissues. Special storage and handling is required to maintain their effectiveness and biosafety standards.
Opportunity: With the growing geriatric population suffering from chronic wounds and diabetes, the demand for advanced wound care therapies is rising rapidly. Acellular dermal matrices help address an unmet need for treating complex and non-healing wounds. Favorable reimbursement policies also support their increased adoption. Innovation in production technology may help reduce material costs and further strengthen clinical outcomes.
Threats: Stringent regulatory frameworks impact product development timelines and market entry. Storage and transportation challenges can affect product availability. Alternative therapies like bioengineered skin substitutes and growth factors pose competition. Restrictions during the COVID-19 pandemic posed supply chain and logistic issues impacting sales.
Key Takeaways
The U.S. Acellular Dermal Matrices Market Size is expected to witness high growth driven by the rising incidence of diabetic foot ulcers and pressure sores. The global U.S. Acellular Dermal Matrices Market is estimated to be valued at US$ 2783.32 Mn in 2023 and is expected to exhibit a CAGR of 5.5% over the forecast period 2023 to 2030.
North America currently dominates the market owing to the presence of advanced healthcare infrastructure and availability of reimbursement. With over 10% of its population aged 65 years and above, the U.S. faces a growing economic burden of treating chronic wounds. This high prevalence of conditions treatable by acellular dermal matrices will fuel market expansion in the country during the forecast period. The Asia Pacific region is expected grow at the fastest pace owing to factors like the improving access to advanced wound care therapies and a surge in the diabetic patient pool in highly populous emerging countries like India and China. Several market players are also focusing on expanding their presence in Asia to tap the potential opportunities.
Key players related content comprises: Key players operating in the U.S. acellular dermal matrices market are Biomet, Inc., Wright Medical Technology, Inc., Smith & Nephew Plc, and Stryker. These companies are focusing on new product launches, forging strategic collaborations and enhancing their manufacturing and distribution capabilities in the country to strengthen their market position.
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