Bacteriophage therapy, also known as phage therapy, is the therapeutic use of bacteriophages to treat pathogenic bacterial infections. Phage can be administered for both internal and external use to treat infections like bacterial diarrhea, ulcers, food poisoning, respiratory infections, as well as ear, eye, and skin infections. Phage therapy is considered promising because phage are non-toxic to humans with very few side effects.

The global bacteriophage therapy market is estimated to be valued at US$ 1280.9 Mn in 2023 and is expected to exhibit a CAGR of 8.6% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market Dynamics:
Rising incidences of antimicrobial resistance (AMR) have fueled the demand for alternative treatment options. Bacteriophage therapy is gaining traction as AMR renders many conventional antibiotics ineffective. According to the Centers for Disease Control and Prevention (CDC), more than 2.8 million antibiotic-resistant infections occur in the U.S. each year, with more than 35,000 deaths as a direct result. Growing antibiotic resistance has prompted increased research in phage therapy as bacteriophages can effectively kill antibiotic-resistant bacteria. Other drivers such as demand for cost-effective and minimally invasive treatment options are also stimulating market growth. However, lack of standardized production and quality control protocols pose challenges to widespread adoption of phage therapy.

SWOT Analysis
Strength: Bacteriophage therapy has several advantages over traditional antibiotics. It specifically targets drug-resistant bacteria without harming other microbes. This precision targeting helps avoid side effects often caused by broad-spectrum antibiotics. Bacteriophages replicate on site to continue fighting the infection, requiring fewer repeat treatments than antibiotics.
Weakness: Regulatory pathways for approval of bacteriophage products have not been standardized. Long term safety and efficacy data is still limited. Producing phage on a large scale requires optimization of manufacturing processes.
Opportunity: The global rise of antimicrobial resistance presents a large opportunity for alternative treatments like bacteriophage therapy. Growing public awareness about overuse of antibiotics may increase acceptance of phage-based therapeutics. Emerging viral sequencing technologies could aid rapid development of targeted phage cocktails.
Threats: Patient immunity or resistance mechanisms may eventually limit effectiveness of certain bacteriophage formulations. Approval delays due to regulatory complexities threaten the commercial viability of some companies. Competing drug classes with established markets may slow initial adoption.

Key Takeaways
The global Bacteriophage Therapy market scope is expected to witness high growth over the forecast period of 2023 to 2030. The market size is forecasted to reach US$ 1280.9 Mn in 2023 registering a CAGR of 8.6%.

Regional analysis: North America dominates the global Bacteriophage Therapy market currently and is expected to maintain its dominance over the forecast period. Availability of advanced healthcare facilities and growing R&D investment in the US and Canada are major factors contributing to the large share of North America. Asia Pacific is poised to witness the fastest growth owing to rising antimicrobial resistance, improving healthcare infrastructure and increasing government support for alternative treatments in countries like India and China.

Key players: Key players operating in the Bacteriophage Therapy market are Armata Pharmaceuticals, Inc., Pherecydes Pharma, Eliava Biopreparations, Intralytix, Phagelux, Inc., Adaptive Phage Therapeutics, PhagePro, Inc., InnoPhage, Inc., Pherecydes Pharma. Armata Pharmaceuticals and Pherecydes Pharma are focusing on expanding their product portfolios and manufacturing capabilities through acquisitions and collaborations.

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