The bioreactors market is used in various applications including cell therapy, tissue engineering, and biomanufacturing. Bioreactors help mimic natural physiological conditions to support living microbial, mammalian or plant cell growth while maintaining optimal cell functions such as proliferation and protein production. They are used for large-scale production of antibiotics, vaccines, monoclonal antibodies, and recombinant proteins among others.
The Global bioreactors market is estimated to be valued at US$ 23.62 Bn in 2024 and is expected to exhibit a CAGR of 11% over the forecast period 2024 to 2030.
Bioreactors provide controlled environments required for growth of cells and help produce high-quality and high-yield cell products. They find wide usage in R&D, monoclonal antibody production, vaccine manufacturing and cell and gene therapy.
Market Drivers
High prevalence of chronic diseases is a key factor fueling demand for bioreactors. According to WHO, chronic diseases accounted for 60% of the 56.5 million total reported deaths globally in 2016. Bioreactors are extensively used for producing new treatment modalities including cell and gene therapies, tissue engineering products and biopharmaceuticals to treat chronic conditions more effectively. Growing demand for biotherapeutics such as monoclonal antibodies is also propelling the need for scaled-up bioreactor solutions having higher yields.
The current geopolitical situation is impacting the growth of the bioreactors market in various ways. With rising geopolitical tensions and restrictions on trade between some major countries, the supply chain for bioreactors has been disrupted to some extent. Countries are focusing more on self-reliance and indigenous production of bioreactors to meet domestic demands. This has both positive and negative effects. On one hand, it can boost the bioreactors manufacturing capacities of some countries. However, protectionist policies also restrict imports and exports between countries, affecting global market growth.
With growing nationalist sentiments globally, countries want to develop their own biomanufacturing hubs and reduce dependencies on other geographies. This has led governments to increase funding for setting up local biomanufacturing facilities. While it promotes regional growth, the overall market may see a slowdown if major trading partners adopt an isolationist approach. The bioreactors industry needs to diversify production locations worldwide and establish multiple regional supply chains to minimize risks from geopolitical uncertainties. Developing economies need incentives and partnerships to build their biomanufacturing capabilities and emerge as new bioreactors growth centers over the forecast period.
North America currently holds the largest share of the global Bioreactors Market Growth owing to strong government support and presence of major players. Europe and Asia Pacific are other concentrated markets, driven by their pharmaceutical manufacturing industries. However, China is emerging as the fastest growing regional market propelled by government biotech initiatives and growing outsourcing of production activities by multinational companies seeking to expand capacities. Other South Asian countries are also encouraging investments in the biomanufacturing sector to fulfill rising healthcare demands and become important bioreactors markets of the future.
When it comes to geographical revenues, North America dominates the bioreactors market holding around 40% share led by the US. The regional market benefits from stringent quality standards, availability of resources, and well-developed infrastructure to support large-scale biomanufacturing. Europe accounts for over 30% share on the back of government incentives for life sciences R&D and commercial manufacturing in countries like Germany, UK, France and Switzerland. However, Asia Pacific is identified as the fastest growing geographical market for bioreactors propelled by increasing healthcare expenditure, domestic consumption, and cost competitiveness in China and India. The region sees substantial investments from pharmaceutical giants aiming to tap the opportunities in these emerging biotech hubs.
Key Takeaways
Key players operating in the bioreactors market are Pfizer, Inc., Novartis AG, Kite Pharma, Inc., Bluebird bio, Inc., Becton Dickinson and Company, Amgen, Inc., Vericel Corporation, uniQure N.V., Spark Therapeutics, Inc., Renova Therapeutics, Orchard Therapeutics plc, Kolon Tissue Gene, Inc., Human Stem Cell Institute, Dendreon Pharmaceuticals, Helixmith Co., Ltd (ViroMed Co., Ltd), Bausch & Lomb Incorporated, and Castle Creek Biosciences, Inc (Fibrocell Technologies, Inc.), among others.
The growing demand in cell therapy and T-cell manufacturing is expected to drive the bioreactors market during the forecast period. Bioreactors are widely used in manufacturing of CAR T-cells, which has increased exponentially in recent years due to success in treatment of hematologic malignancies. Moreover, rising number of clinical trials for cell therapies will also augment market growth.
Globally, North America dominates the bioreactors market due to increased funding for cell-based research in the region. However, Asia Pacific region is likely to witness highest growth rate over the forecast period owing to rising biologics manufacturing in countries such as China and India along with growing stem cell research in the region.
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