Advances in Implantable Medical Devices
Polymeric biomaterials have expanded implant applications thanks to enhanced biocompatibility and mechanical properties. They are widely used in dental and orthopedic implants. Polyethylene and PEEK are used in joint replacements like artificial hips, knees and shoulders due to their toughness and corrosion resistance.
Bioresorbable polymeric implants made of polylactide and polycaprolactone degrade gradually after fulfilling their function, eliminating the need for implant removal. This has benefits for pediatric applications. Other advances include drug-eluting stents made of polyurethanes and polyesters that steadily release medications to prevent restenosis post angioplasty. Implantable cardiac pacemaker and defibrillator polymer shells ensure longevity and biocompatibility.
Custom polymeric sutures developed using absorbable synthetic aliphatic polyesters reduce infections and promote healing compared to traditional sutures. This technology is transforming wound closure procedures. Future innovation focuses on 3D-printing biodegradable polymeric implants personalized for individual patients.
Impact of Polymeric Biomaterials on Drug Delivery
Controlled and targeted drug delivery systems have significantly improved healthcare using Global Polymeric Biomaterials . Biodegradable polyesters like polylactic acid and polyglycolic acid are extensively researched for sustained release applications. They are fabricated into microparticles, nanofibers and films delivering anticancer drugs, vaccines, hormones, growth factors and antibiotics over weeks to months.
Advanced hydrogel systems enable on-demand drug release through external triggers like temperature, light, electricity or enzymes. Thermosensitive injectable hyaluronic acid hydrogels act as depots at the site of action. Polymeric contact lenses simultaneously treat ocular conditions and deliver eye drops at a controlled rate for days without redosing. This improves patient compliance. Novel vaginal drug delivery rings aid contraception and HIV prevention. The future promises "smart biomaterials" that release payloads specifically in response to disease biomarkers.
Addressing Global Healthcare Challenges
Polymeric biomaterials are expanding access to quality healthcare globally. Biodegradable sutures and implants have significantly reduced costs of surgery in developing nations. Their widespread deployment is bridging disparities in medical access.
Polymeric drug delivery systems promise sustained treatment of chronic conditions like diabetes and hypertension at affordable costs using single dosing. This can transform management of non-communicable diseases prevalent in rural communities lacking healthcare infrastructure and repeated medication access.
Innovative applications in biomaterials are developing prosthetics, dressings and scaffolds from agricultural waste polymers as alternatives to expensive synthetic options. Bioprintingtechnology also utilizes natural and synthetic polymers to manufacture affordable tissues and organs addressing shortage globally. With continued research and development, polymeric biomaterials hold promise to democratize cutting-edge medicine worldwide.
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