L-Ergothioneine Or EGT Is A Unique And Uncommon Amino Acid Found In...

L-Ergothioneine Or EGT Is A Unique And Uncommon Amino Acid Found In Nature

Posted 2024-04-04 12:58:57

The While it was first isolated in 1909 from the mushroom Clitocybe illudens, scientists are still uncovering its widespread benefits and importance for human health. This article aims to provide an overview of EGT, where it is found, its antioxidant properties, roles in cellular health, and benefits against oxidative stress and aging.

What is EGT?
L-ERGOTHIONEINE (EGT) is a uniquely water-soluble thiol (sulfur-containing) compound that is synthesized only by certain fungi, bacteria and plants. Unlike other cellular antioxidants like glutathione, EGT is not produced by animals or humans and needs to be obtained through diet. EGT contains an unusual chemical structure that allows it to powerfully and selectively neutralize oxidative stress within cells. Some key facts about EGT include:

- Chemical formula is C10H16N2O2S
- Very stable even under extreme pH and temperature conditions
- Concentrated in tissues with high levels of oxidative metabolism
- Found naturally in mushrooms, fungi, plants, and meats from animals that graze on EGT-containing plants
- Functions as a "redox reserve" antioxidant within cells

Where is EGT Found Naturally?
While mushrooms are often considered the best dietary sources of EGT, it is also present in significant amounts in other plant and animal foods:

- Mushrooms - Oyster, Shiitake and white button mushrooms contain very high amounts from 50-800mg per 100g.
- Fungi - Mushroom fermentation byproducts contain concentrated EGT.
- Grains - trace amounts found in wheat, rice and barley.
- Meat - Beef and poultry from grass-fed cattle contain fair amounts as grazing animals consume EGT-rich grasses and plants.