Daten aus dem Cache geladen. Ebola Vaccine: Making Strides Forward in the Race to Create an...

Ebola Vaccine: Making Strides Forward in the Race to Create an Effective Ebola Vaccination Recent Advancements

0
683

The Ebola virus was first discovered in 1976 during simultaneous outbreaks in what is now the Democratic Republic of the Congo and South Sudan. Since then, periodic outbreaks have occurred across central Africa. The 2013-2016 West African epidemic brought widespread international attention as it caused over 28,000 cases and 11,000 deaths. This outbreak demonstrated the need for a licensed Ebola Vaccine  to help control future epidemics. Several vaccines had been in development since the 1990s but none had completed clinical trials at the start of the West African outbreak.

Early Vaccine Candidates

Some of the earliest vaccine candidates included live attenuated and inactivated virus approaches. A live attenuated vaccine called the Zaire ebolavirus vaccine (ZEBOV) was tested in primates in 1996 and conferred full protection against infection. However, concerns over potential reversion to virulence hindered its progression. Inactivated virus vaccines were also studied but required high antigen doses and multiple immunizations to achieve protection in primates. DNA vaccines were another early approach using plasmid DNA to express Ebola viral proteins and induce immune responses. While stimulating antibody and cellular immunity, DNA vaccines provided inconsistent protection in primate studies.

Get more insights on - Ebola Vaccine

Search
Categories
Read More
Other
Brazed Plate Heat Exchanger Market 2024-2032: Technological Advancements and Market Demand
The brazed plate heat exchanger market has emerged as a key segment within the global heat...
By Rutuja Patil 2024-11-06 10:28:28 0 193
Other
Tech Titans: The 2024 Roundup
The year 2024 has been marked by significant advancements in technology, particularly in AI, IoT,...
By John Martech 2025-01-03 07:18:34 0 11
Networking
Promo Gifts As Marketing Tools
Understanding your goal market. Frequently people think they can be everything to everybody else...
By Syedaliahmad Syedaliahmad 2023-05-02 10:35:18 0 1K
Other
Formic Acid Market Size, Share, Segmentation, Drivers and Overview 2024-2030
The global formic acid market size was valued at USD 2,315.6 million in 2023 and is poised to...
By Manisha Bommagoni 2024-08-16 09:39:44 0 449
Health
The psychological impact of masturbation.
オナニーによる副作用の真実  ...
By Beyourlover111 Beyourlover111 2023-09-19 07:26:06 0 2K