Epidermolysis Bullosa Market is Anticipated to Witness High Growth...

Epidermolysis Bullosa Market is Anticipated to Witness High Growth Owing to Rising Awareness and Government Support

Posted 2024-08-16 12:33:32

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Epidermolysis bullosa (EB) is a rare genetic disease which causes easy blistering of the skin and mucous membranes. Patients suffering from EB have extremely fragile skin that can blister or tear from minor friction or trauma. The symptoms range from minor local blistering to severe physical wounds covering large areas of the body. EB currently has no cure and treatment is focused on symptom management through specialized wound care, pain management, and preventing infections. The global EB market has witnessed significant growth in the last few years owing to increasing government initiatives aimed at improving disease awareness and providing support to patients. Additionally, rising research investments towards developing novel treatment options will further aid market expansion over the coming years.
The Global Epidermolysis Bullosa Market is estimated to be valued at US$ 3,429.30 Mn in 2024 and is expected to exhibit a CAGR of 11.% over the forecast period 2023 to 2030.

Key Takeaways
Key players operating in the Epidermolysis bullosa market are Amryt Pharma, Abeona Therapeutics, Castle Creek Pharmaceuticals, RegeneRx, Krystal Biotech, RHEACELL GmbH, Holostem Terapie Avanzate, StemRim/Shionogi, and Phoenix Tissue Repair.
Over the past few years, key companies have focused on advancing their product pipelines through active research on drug candidates targeting the underlying genetic causes and disease manifestations of EB. For instance, Amryt Pharma is developing a gene therapy candidate (Filsuvez) for recessive dystrophic EB and Krystal Biotech is developing an ex-vivo gene therapy (KB103) to treat dystrophic and junctional EB.
The global Epidermolysis bullosa market is also expected to witness significant growth in emerging nations such as China, India, Brazil and Mexico. This is attributed to the growing patient pool along with increasing healthcare reforms and expenditure to support rare disease treatment in these countries. For example, the Chinese government has implemented various initiatives such as designating over 200 rare diseases as 'priority review' to provide priority review vouchers, funding and tax incentives for orphan drug development.

Market Drivers
High prevalence of different EB subtypes globally - It is estimated that over 500,000 people worldwide are affected by EB, thereby creating a substantial patient population requiring specialized treatment and management.
Growing orphan drug development - Multiple drugs and therapies are in clinical trial phases targeting the genetic roots and symptoms of different EB types, including gene therapies, pharmacological chaperones, and skin substitutes. Positive trial results will significantly aid the EB market potential.

Market Restrain
Lack of effective treatments and high costs - Most existing therapies only provide symptomatic relief and come with significant costs associated. Absence of curative treatment options has historically limited the EB therapeutics market size.
Rarity of disease - With low prevalence of individual EB subtypes, it is challenging for companies to fully recoup investment costs involved in orphan drug development and commercialization. This poses a barrier to rapid industry growth.

Segment Analysis
The dystrophic epidermolysis bullosa (DEB) sub segment dominates the epidermolysis bullosa market currently. This is because DEB is the most severe and most common form, accounting for over 50% of all EB cases. Patients with DEB often have widespread blistering, scarring, and contractures due to fragility of the skin and mucous membranes.

Global Analysis
The North America region currently holds the largest share in the epidermolysis bullosa market and will continue to dominate during the forecast period. This is attributed to increased health awareness, higher healthcare spending, growing EB patient pool, and presence of key players in the region. Asia Pacific is projected to be the fastest growing region owing to large patient population, rising healthcare expenditure, growing cases of EB due to genetic disorders and government initiatives to spread awareness about EB treatment in countries such as China and India.

Priya Pandey is a dynamic and passionate editor with over three years of expertise in content editing and proofreading. Holding a bachelor's degree in biotechnology, Priya has a knack for making the content engaging. Her diverse portfolio includes editing documents across different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. Priya's meticulous attention to detail and commitment to excellence make her an invaluable asset in the world of content creation and refinement.

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