B. Reducing Enemy Resistances
Elemental Penetration: Reducing elemental resistances can help bypass some of the effectiveness limitations caused by ailment resistance.

Elemental Weakness curse, Conductivity, or Path of exile currency Flammability curses lower enemy resistances, allowing ailments to apply more reliably.
Shock Effectiveness: While many enemies resist Shock, including bosses, increasing the effectiveness of Shock through passive nodes and items like Vaal Lightning Trap or Yoke of Suffering can still allow you to shock resistant or immune targets.

C. Strategies to Overcome Ailment Immunity
Alternate Damage Sources: If you rely heavily on ailments like Ignite or Freeze for damage, consider incorporating secondary damage sources that aren’t dependent on ailments. Skills that deal raw elemental damage without relying on ailment application can still deal significant damage.

Scaling Raw Damage Over Time: For buy POE orbs builds focusing on Ignite, scaling raw fire damage over time with items like The Taming or Emberwake rings can help deal significant damage even if some enemies are resistant to Ignite.