Among patients infected with the new coronavirus, some people will have the situation that the new coronavirus breaks through the blood-brain barrier and invades the brain. Studies have confirmed that the virus can break through the human blood-brain barrier, infect brain cells, and cause neurodegeneration to further develop into brain neuroinflammation. Infection with the novel coronavirus has been reported to cause loss of gray matter in the left hemisphere of the brain.
Elevated levels of the inflammatory marker IL-6 in the brain lead to a reduction in the volume of the brain's hippocampus. These brain lesions can destroy memory and cognition, also known as long covid brain fog. Patients with Long COVID-19 memory loss also develop brain damage as it shows up on CT images while being tested. For patients infected with the new coronavirus, sometimes the new coronavirus in the body may not be completely cleared, and a small amount of virus remains.
In this case, when the virus is only temporarily suppressed by the immune system and the rest is not in the nasopharyngeal area, the PCR test will be negative. The residual virus will continue to infect the endothelial cells of multiple organs in the human body, forming tiny thrombi between the cells, and then producing a wide-ranging inflammatory response. The inflammatory response resulted in elevated pro-inflammatory markers, including ferritin, coagulation protein VIII, and C-reactive protein (CRP), as well as increased D-dimer. D-dimer levels are associated with acute ischemic stroke, especially cryptogenic stroke.
According to How To Get Rid Of Long Covid-19 Brain Fog?, people infected with the new coronavirus may have taken steroids and antibiotics, such as Long use of glucocorticoids, if they develop severe symptoms during infection. But studies report that Long use of glucocorticoids may alter the function and structure of the hippocampus, leading to memory loss.
People infected with the new coronavirus have severe hypoxia and other symptoms during the infection period. Novel coronavirus 1 invades the brain, causing cerebral microvascular blockage, causing symptoms similar to minor ischemic stroke or hemorrhagic stroke, resulting in memory loss.
Patients infected with the novel coronavirus are prone to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) with sudden or gradual onset of persistent disabling fatigue and post-exertional malaise (PEM). This reduces the patient's body's metabolism, leading to neuroinflammation in hypometabolic lesions. A PET study examining seven patients with persistent cognitive and mood impairment 6 months after recovery from COVID-19 encephalopathy found hypometabolism in the anterior cingulate and insular cortices, as well as in the caudate cortex. This can also lead to memory loss.
Through PET (Positron Emission Tomography, which detects the development of the disease by detecting the level of human metabolism) imaging analysis of the brains of 15 patients with new coronary pneumonia who are in the subacute stage and have abnormal sense of smell and taste, Jonas of the University Medical Center Freiburg, Germany Prof. A. Hosp's team found that 10 patients had decreased metabolism in the frontoparietal lobe.
Gwena ëlle Douaud's team at the Wellcome Center for Integrative Neuroimaging (WIN), University of Oxford, UK, systematically analyzed brain imaging data of 401 patients with coronavirus infection before and after infection, and found that coronavirus infection caused greater reduction in gray matter thickness and orbitofrontal cortex and hippocampus Tissue contrast in the paragyrus, regions associated with primary olfactory cortex function showed more tissue damage, and greater brain volume loss. If you are suffering from long covid brain fog, please contact LongCovidCareCenter promptly for the best post covid brain fog treatment.
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