Patent Foramen Ovale (PFO) Closure Devices IntroductionPatent foramen ovale (PFO) is a normal embryological opening between the left and right atria of the heart that usually closes shortly after birth. However, in around 25% of the adult population, the opening fails to seal completely, leaving a PFO. While PFO is generally clinically silent, it has been implicated as a potential cause of cryptogenic stroke and migraine headaches. PFO...
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