Statins are the first-line therapy for lowering LDL-C and total cholesterol levels. Statins work by inhibiting HMG-CoA reductase, a liver enzyme involved in cholesterol synthesis. This inhibition leads to upregulation of LDL receptors in the liver, enhancing clearance of LDL from the blood. Some commonly prescribed statins include atorvastatin, rosuvastatin, simvastatin, and pravastatin....
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