There are five classes of them - IgG, IgM, IgA, IgD, and IgE - which differ in their heavy chain structure and effector functions. IgG is the most abundant antibody in the blood and extracellular fluid. It can cross the placenta and provides protection to fetuses and newborns. IgM is usually the first antibody produced during early-stage infections as it activates the complement system more...
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