Peptide Synthesis: Overview of Methods for Producing Biologically Active Molecules
One of the most common methods for synthesizing peptides is solid phase peptide synthesis (SPPS). In SPPS, the first amino acid is attached to an insoluble polymer support. Additional amino acids are then added stepwise to elongate the peptide chain still attached to the solid support. SPPS has several advantages over solution phase synthesis including easy purification by simple washing and...
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