Tattoo Numbing Cream: How Emla numbing cream Can Make Getting Inked Less Painful What is Tattoo Numbing Cream?Emla numbing cream is a topical anesthetic cream designed to reduce pain and discomfort during the tattooing process. The main active ingredient in most numbing creams is lidocaine, which works by blocking nerve signals from being transmitted to the brain. When applied to the skin area that will be tattooed, lidocaine interferes with the perception of pain.How Does...