Codeine: A widely used opioid analgesic medication
Historical background of codeineCodeine is one of the oldest medications still widely used today. It was first isolated from opium in 1832 by Pierre Robiquet, a French chemist and pharmacist. Codeine was one of the earliest semi-synthetic opioids to be developed from morphine via methylation. However, its analgesic effects were not widely explored or utilized until the late 19th century. It...
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