Advances in Bird Flu: A Looming Global Health Threat and Vaccine Strategies History and Origin Avian influenza viruses have been around for a long time and have caused disease in many bird species for over 100 years. The earliest known major outbreak of bird flu in poultry occurred in Italy and Egypt in the early 1900s. New subtypes were identified during outbreaks in chickens in Scotland in 1959 and Pakistan in 1994. The H5N1 strain that is currently of greatest human...
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