Recent Advances in Treating Metastatic Melanoma Therapeutics Immunotherapies have revolutionized the treatment landscape for metastatic melanoma over the past decade. Checkpoint inhibitors like ipilimumab, nivolumab, and pembrolizumab work by removing the brakes on the immune system allowing T cells to recognize and attack cancer cells. Ipilimumab was the first FDA-approved immunotherapy for metastatic melanoma in 2011. It works by targeting CTLA-4, a...
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