The pooled DOR was 3.26 (95% CI -0.29, 6.82). A subgroup analysis of HIV-infected men who have sex with men (MSM) demonstrated a pooled sensitivity of 0.75 (95% CI 0.28, 0.96). p16/Ki67 dual immunostaining might have a higher sensitivity for detecting AIN in HIV-infected MSM. p16/Ki67 dual immunostaining might be more sensitive in HIV-infected MSM and has higher specificity compared to human papillomavirus testing among this high-risk group. p16/Ki67 dual immunostaining might be an adjuvant and potential triage test for anal cytology in anal cancer screening.Incidents of violence among intimate partners remains an increasing concern in Nigeria. More disturbing is the fact that some women still justify acts of violence (particularly, wife-beating) from their partners. The purpose of this study is to investigate the impact of spousal demographic gap and other specific demographic constructs in explaining women's justification of wife-beating. The study is based on married or cohabiting women sampled in the 2018 Nigeria Demographic and Health Survey. The study shows that, overall, 31% of women justified wife-beating. The proportion of women justifying wife-beating ranges from as low as 1% to as high as 89% across the 36 States. Using Binary Logistic Regression, partners' age difference was not a significant predictor. However, when a woman's education level is at par (OR = .844, p less then .05) or higher than that of her partner (OR = .726, p less then .000), she is less likely to believe that a man is justified to beat his wife under any circumstances. Other factors explaining the justification of wife-beating among married and cohabiting women are economic status, place of residence, employment status of partners, and women's involvement in decision-making. The findings reveal the association between spousal demographic gap and women's justification of wife-beating. Programs that address individual and structural factors promoting justification of wife-beating become necessary.A pilot Multi-Agency Stalking Intervention Programme (MASIP), introduced in three police forces in England, provided among a range of interventions, the delivery of safety planning advice, and needs-based support for stalking victims through a bespoke advocacy service. The ultimate aim of MASIP was to equip victims with tools to manage the variety of harms caused by stalking, as well as enable them to access the criminal justice system with adequate support. This study explores the personal needs of stalking victims from the perspectives of stalking victims, advocates and stakeholders involved in the intervention program, as part of a larger evaluation study conducted by the authors. Semi-structured interviews were conducted with a total of 10 stalking victims who participated in the MASIP, three advocates who directly interacted with the victims, and 19 MASIP stakeholders involved in the project. Findings revealed that overall, victims believed the advocacy service aided their ability to cope with the realities of stalking. Having a victim advocate as single point of contact made victims' journey through the justice system easier to navigate, provided them with the emotional support that they required to deal with the harms of stalking and the practical advice offered regarding their personal safety, and allowed them to feel in control of their own risk management. Advocates reported that the multi-agency context helped in risk assessment and ability to design and deliver bespoke support plans, which uniquely improved victims' engagement with the service. https://www.selleckchem.com/products/geldanamycin.html Due to the small size and possibly biased sample, our conclusions must be interpreted with caution. Renin-angiotensin system inhibitors (RASi) reduce mortality among heart failure (HF) patients, but their effect among those complicating contrast-induced acute kidney injury (CI-AKI) remains unexplored. We aimed to investigate whether the relationship between RASi prescription at discharge and mortality differs between HF patients with or without CI-AKI following coronary angiography (CAG). About 596 HF patients from an observational cohort were divided into a CI-AKI group (  = 104) and a non-CI-AKI group (  = 492) based on whether they had CI-AKI following CAG. The endpoint was all-cause mortality. Multivariable Cox regression was performed in each group to explore the associations between RASi at discharge and mortality. During the median follow-up time of 2.26 (1.70; 3.24) years, higher mortality rate was observed in the CI-AKI group compared to the non-CI-AKI group (18.3% vs 8.9%,  = 0.002). Among HF patients with CI-AKI, after adjusting for confounding factors, the association was not significant between RASi prescription at discharge and mortality (HR 0.39, 95%CI 0.12-1.31,  = 0.128), while it was among those without CI-AKI (HR 0.39, 95%CI 0.18-0.84,  = 0.016). RASi prescription at discharge for HF patients complicating CI-AKI tended to be ineffective, while it benefited those without CI-AKI. Further randomized evidence is needed to confirm this trend. RASi prescription at discharge for HF patients complicating CI-AKI tended to be ineffective, while it benefited those without CI-AKI. Further randomized evidence is needed to confirm this trend.The Transdisciplinary Collaborative Center (TCC) in Precision Medicine for Minority Men's Health was established at the Medical University of South Carolina (MUSC) in 2015 to address disparities in the translation of precision medicine approaches among racial minority groups. This regional consortium focuses on three primary areas (1) the development of a consortium of regional and national partners, (2) conducting transdisciplinary research examining synergistic effects of biological, social, physiological, and clinical determinants of chronic disease risks and outcomes, and (3) dissemination and implementation of precision medicine approaches, with an emphasis on reducing disparities in health care and outcomes among minority men. Given consistent calls to better translate precision medicine approaches and the focus of this consortium on addressing disparities among minority men, we provide an overview of our experience in developing the MUSC TCC, including barriers and facilitators to conducting translational research on minority men's health issues in the context of precision medicine.