Although centralization of cancer care would require altering referral patterns, decision-support resources may help patients make informed choices. While most participants were directed to their cancer surgeon, active participants tended to select NCI-designated/academic hospitals. Although centralization of cancer care would require altering referral patterns, decision-support resources may help patients make informed choices. Black individuals and individuals of low socioeconomic status are at increased risk for obstructive sleep apnea (OSA). The Berlin Questionnaire is one of the most widely used screening tools for OSA; however, there is limited research on its diagnostic accuracy in low-income, Black populations. This study analyzed data from an ongoing study taking place among a cohort from two predominantly Black neighborhoods in Pittsburgh, PA (96.3% Black, 79.6% female). The sample included 269 individuals without a prior diagnosis of OSA who completed the Berlin Questionnaire and also participated in a home sleep apnea test (HSAT). An apnea-hypopnea index (AHI) ≥ 15 was used to identify individuals with moderate or severe OSA. 19.3% of individuals met criteria for moderate to severe OSA based on HSAT, while 31.2% of participants screened as high risk for OSA based on the overall Berlin index. Using AHI>=15 as the reference standard, the Berlin Questionnaire had a sensitivity of 46.2%, specificity of 72.4%, positive predictive value (PPV) of 28.6%, and negative predictive value of 84.9% among this sample. Analyses stratified by sex suggested that the Berlin Questionnaire had better diagnostic validity in women than men. The Berlin Questionnaire has lower sensitivity and PPV in our sample than those observed in general population samples. The measure performed better among women, though a higher proportion of men fell into the moderate or severe OSA range based on the HSAT. Given the significant downstream consequences of OSA, utilizing screening tools that better detect OSA in Black communities is key. The Berlin Questionnaire has lower sensitivity and PPV in our sample than those observed in general population samples. The measure performed better among women, though a higher proportion of men fell into the moderate or severe OSA range based on the HSAT. Given the significant downstream consequences of OSA, utilizing screening tools that better detect OSA in Black communities is key. Sleep-disordered breathing is an increasingly identified condition in the pediatric population, resulting in an increasing number of direct to lab referrals for polysomnography (PSG). We present a unique case of a pediatric patient who demonstrated continuous hypoxemia during PSG. A 6-year-old African American female presented for PSG via direct referral for concern of obstructive sleep apnea (OSA). At the onset of the PSG, SaO₂ of 85% while awake and at rest was noted. The SaO₂ did not improve despite trouble shooting, probe and patient repositioning, or probe replacement. The PSG demonstrated an average sleep SaO₂ of 81%, with SaO₂ nadir of 73% and apnea-hypopnea index (AHI) = 6.1 events/h, consistent with mild OSA with persistent desaturation. Hemoglobin electrophoresis was consistent with hemoglobin Louisville. This case illustrates that communication between the sleep medicine physician and the community physician after a direct to lab referral is crucial to avoid concern and confusion. Sleep-disordered breathing is an increasingly identified condition in the pediatric population, resulting in an increasing number of direct to lab referrals for polysomnography (PSG). We present a unique case of a pediatric patient who demonstrated continuous hypoxemia during PSG. A 6-year-old African American female presented for PSG via direct referral for concern of obstructive sleep apnea (OSA). At the onset of the PSG, SaO₂ of 85% while awake and at rest was noted. The SaO₂ did not improve despite trouble shooting, probe and patient repositioning, or probe replacement. The PSG demonstrated an average sleep SaO₂ of 81%, with SaO₂ nadir of 73% and apnea-hypopnea index (AHI) = 6.1 events/h, consistent with mild OSA with persistent desaturation. Hemoglobin electrophoresis was consistent with hemoglobin Louisville. This case illustrates that communication between the sleep medicine physician and the community physician after a direct to lab referral is crucial to avoid concern and confusion. Short sleep duration (SD) is associated with cardiovascular disease (CVD). We investigated the relationship between objective SD and subclinical atherosclerosis employing hybrid PET/MRI with F-FDG tracer in the MESA cohort. We utilized data from MESA-SLEEP and MESA-PET ancillary studies. SD and sleep fragmentation index (SFI) were assessed using 7-day actigraphy. The primary and secondary outcomes were carotid inflammation, defined using target-to-background ratios (TBR), and measures of carotid wall remodeling (carotid wall thickness [CWT]), summarized by SD category. https://www.selleckchem.com/products/tunicamycin.html Multivariate linear regression was performed to assess the association between SD and SFI with the primary/secondary outcomes, adjusting for several covariates including apnea-hypopnea index (AHI), and CVD risk. Our analytical sample (n=58) was 62% female (mean age 68±8.4 years). Average SD was 5.1±0.9 hours in the short SD group (≤6 hours/night, 31%), and 7.1±0.8 hours in the normal SD group (69%). Prevalence of pathologic vascular infenerating but suggest that both habitual SD and SFI should be investigated in future studies as potential risk factors for subclinical atherosclerosis. In Portugal, requirements for selection and training of General Practice trainers vary across the different regions of the country. The aim of our study was to assess the satisfaction of general practice trainees with their trainers of the Lisbon and Tagus Valley Regional Health Administration. General Practice trainees were the target population for our cross-sectional, exploratory study. The authors developed a 16-item questionnaire based on the existing literature. The questions covered the following domains patient safety, learning environment, trainer's feedback, the trainee/trainer relationship, assessment of educational progress and continuous professional development of trainers. Items were scored on a 5-point Likert-type scale. Data was collected at a meeting in October 2018 attended by General Practice trainees. A total of 384 questionnaires were distributed, with a response rate of 59.9%. The majority of respondents were female (79.9%) and all years of specialty training were represented. Our study shows that 60.