CONCLUSION Hyperglycemia, non-homogenous OLK, location of the lesion on the ventral surface of the tongue or floor of the mouth, and epithelial dysplasia might be associated with malignant transformation of OLK. This article is protected by copyright. All rights reserved.BACKGROUND Intra-articular (IA) administration of corticosteroids is performed routinely in equine practice. The lung function of severe asthmatic horses has recently been shown to be improved by IA triamcinolone acetonide (TA). We therefore hypothesised that IA methylprednisolone acetate (MPA), another commonly used corticosteroids, would also decrease the airway obstruction in severe asthmatic horses. OBJECTIVES To compare the effects of intra-articular (IA) and intramuscular (IM) methylprednisolone acetate (MPA) administration on lung function and serum cortisol levels in horses with severe asthma. STUDY DESIGN Randomised and controlled experiments on severe asthmatic research animals. METHODS Severe asthmatic horses in exacerbation were administered 200 mg of MPA either intramuscularly (n = 6) or via intra-articular injections in the tarsocrural joints (n = 6; 100 mg/joint). Serum cortisol concentration and pulmonary function was measured for 8 days. RESULTS A significant decrease in pulmonary resistance in the IA group (p = 0.003, mean diff 1.14) on day 1 in comparison with baseline was observed. A significant decrease from baseline was also observed on serum cortisol values in the IA group 6 hours after injection (p=0.001, mean diff 44.5), and at day 1 (p=0.003, mean diff 45.1). MAIN LIMITATIONS Joint health was not evaluated in the current study and the physiological response of the severe asthmatic horses might deviate from that of the milder forms of asthma. CONCLUSIONS MPA IA administration improves the lung function of severe asthmatic horses. However, this effect was mild and of a short duration. This article is protected by copyright. All rights reserved.Indocyanine Green (ICG) fluorescence imaging has recently been introduced in the field of surgical oncology. The studies published to date have reported its usefulness in detecting hepatic metastases and malignant peritoneal nodules (1-3). This video aims to illustrate the clinical application of ICG with the VisionsenseTM device for fluorescent-guided surgery with a quantitative evaluation. This article is protected by copyright. All rights reserved.OBJECTIVE Anastomotic leakage is a major complication after right hemicolectomy leading to increased morbidity, mortality, length of stay and hospital costs. Previous studies have shown that type of anastomosis (handsewn or stapled) is a major risk factor for anastomotic leakage. The purpose of this study was to evaluate the clinical impact of anastomotic leakage depending on the type of anastomotic technique (handsewn versus stapled). METHODS This was an observational, retrospective, cross-sectional study. Data were collected at two major hospitals in Spain from January 2010 to December 2016. Patients had elective right colectomy for cancer with handsewn or stapled ileo-colic anastomosis. The main outcome was grading of post-operative treatments needed to manage anastomotic leakage according to two major classification systems. The other outcomes were demographics, time of hospitalization, and death rate. RESULTS Patients (n=961) underwent elective surgery for neoplasia of the right colon. Anastomotic leakage was diagnosed in 116 patients (12.07%). Patients with handsewn anastomosis had more Type IIIA surgical complications and received milder treatments than patients with stapled anastomosis who had more Type IIIB complications and more re-laparotomies (p=0.004). The clinical impact of anastomotic leakage was significantly more severe (Grade C) in patients with stapled anastomosis than in patients with a handsewn anastomosis (p=0.007). No differences were found for hospital stay of patients with anastomotic leakage depending on the type of anastomosis (p=0.275). Death due to anastomotic leakage was similar in both groups. CONCLUSIONS The clinical impact of anastomotic leakage in patients with handsewn anastomosis is lower than in patients with a stapled anastomosis. This article is protected by copyright. All rights reserved.BACKGROUND Tracheobronchial foreign body (TFB) aspiration is a significant cause of respiratory problems in children. Timely diagnosis of TFB is important for decreasing the mortality rate and the incidence of complications. Because of advances in radiology, multi-slice spiral computed tomography (MSCT) has become the best technique for diagnosing TFB. METHODS We performed a retrospective study over 5 years from July 2008 to June 2013. We collected information on children who were diagnosed with a TFB by bronchoscopy and analyzed age, sex, location, type of foreign body, and various MSCT manifestations. RESULTS A total of 382 children were included and 68.6% of them were aged 1 to less then 2 years old. The majority (95.8%) of aspirated foreign bodies were vegetation items, and nearly half (47.6%) of them were peanut kernels, followed by sunflower seeds (26.2%). A total of 4.7% of TFBs were in the trachea, 51.0% were in the left main bronchus, and 44.2% were in the right main bronchus. Among the TFBs, 359 (95.5%) showed a high-density shadow in the tracheal/bronchial lumen by MSCT, which could directly establish the presence of a foreign body. https://www.selleckchem.com/products/740-y-p-pdgfr-740y-p.html Emphysema, localized obstruction and pneumonia were more commonly detected in the 7-21d and ≥21d group compared with those in the less then 7d group (all P less then 0.01). Bronchiectasis was found in two children who were diagnosed at least 21 days after aspiration. CONCLUSIONS MSCT has great sensitivity for TFBs. Timely diagnosis and treatment of TFB is important to prevent long-term sequalae in children. This article is protected by copyright. All rights reserved.California's Central Valley, USA is a critical component of the Pacific Flyway despite loss of more than 90% of its wetlands. Moist soil seed (MSS) wetland plants are now produced by mimicking seasonal flooding in managed wetlands to provide an essential food resource for waterfowl. Managers need MSS plant area and productivity estimates to support waterfowl conservation, yet this remains unknown at the landscape scale. Also the effects of recent drought on MSS plants have not been quantified. We generated Landsat-derived estimates of extents and productivity (seed yield or its proxy, the green chlorophyll index) of major MSS plants including watergrass (Echinochloa crusgalli) and smartweed (Polygonum spp.) (WGSW), and swamp timothy (Crypsis schoenoides) (ST) in all Central Valley managed wetlands from 2007-2017. We tested the effects of water year, land ownership and region on plant area and productivity with a multifactor nested analysis of variance. For the San Joaquin Valley we explored the association between water year and water supply, and we developed metrics to support management decisions.