OBJECTIVE Increasing sugar levels in the body which exceeds the normal limit is a metabolic disease commonly called diabetes mellitus. Long-term diabetes mellitus is one of the causes of other diseases such as liver, heart and other body organs. Early diagnosis of diabetes mellitus in a person is very important to know earlier. Early diagnosis is made to prevent other diseases to reduce the occurrence of complications in the body. The use of existing cases can be compared to new cases to diagnose whether the patient has diabetes. METHODS One method that can be used is a case-based expert system which is a reasoning system that uses old knowledge to be compared with new knowledge to overcome new problems. This case-based expert system provides a solution based on the similarity of new cases to existing cases. Some methods that can be used to do the similarity process are Euclidean distance and Nearest neighbor. Old cases taken are cases that have the highest similarity value. Result of the similarity value of a case is considered unsuccessful if it is diagnosed or the target case is less then 80, then the new case will be revised by the expert. RESULTS The test results show that the system is able to recognize diabetes mellitus using the nearest neighbor similarity method, and Euclidean distance similarity with the calculation of accuracy using the euclidean distance similarity method is 93.33% and the nearest neighbor similarity method of 86.67%, So that the euclidean distance method is more effective because it has a higher accuracy value than the nearest neighbor method. OBJECTIVE This research is dedicated toward and develops an educative comic to increase students' awareness in a clean and healthy life for elementary school students in Biankuk Merauke. METHODS Research and Development is used as the method in this research. This research has been done for the grade 2 students of the elementary schools of YPPK Biankuk Merauke with 45 students' subject of research. An educative comic is a specific product that toward in this research. This educative comic also can be used in the learning process. https://www.selleckchem.com/products/SB-202190.html Qualitative and Quantitative data technique analysis is implemented in this research. Scoring, critic and advice that pursued by the learning expert and apprentice in elementary school are as the qualitative analysis technique. On the otherhand, the analysis of students' grade 2 of YPPK Biankuk Elementary school of Merauke questions answering that given is as the quantitative analysis technique. RESULTS This educative comic can be used. It proved by the 97.12% validation score by the education expert in elementary school, that means very valid. 99.04% quality judging score of this educative comic product by the expert and apprentice in elementary education figured as a very valid category. Educative comic product percentage judging score by the students of Biankuk Elementary School of Merauke is 96.67%, very valid category. CONCLUSION This educative comic is very valid and can be used. OBJECTIVE The objective of the research was to determine the giving of Holothuria scabra on the level of Docoxahexaenoic Acid (DHA) of breast milk with preterm chilbirth. METHODS The research was a quasi experimental study with control group design. The samples were postpartum mothers with preterm childbirth consisted of 40 people divided into two groups. Postpartum mothers given Holothuria scabra capsule were intervention group and the postpartum mothers not given Holothuria scabra were control group. The sample of mother's milk of pretest of each group was taken in the seventh day and seven day later the sample was taken 3cc. Intervention was done for 7 days per sample with 3 times dosage consisted of 2 capsules per day. The sample of breast milk was examined with Human DHA ELISA kit. The data were analyzed using Mann-Whitney test and Wilcoxon test. RESULTS The results of the research indicated the difference of DHA level between intervention group and control group with a value of p=value 0.006. After the intervention, the average increase was 187.02μg/mL for intervention group and 7.05μg/mL for control group with a value of 1151.04μg/mL. OBJECTIVE The objective of the research was to investigate the differences of the enzymatic antioxidant serum contents of the catalase on the placenta blood of the low born body weight babies and normal born weight babies. METHODS This was the cross-sectional study research. Samples were taken using the purposive sampling technique, namely the low born body weight babies and normal born weight babies each of which as many as 20 samples. The blood as much as 3cc was taken to examine the enzymatic antioxidant content of the catalase serum using ELISA method. The research was conducted for 3 months. The data were analyzed using Mann-Whitney U test, Chi-Square test, Fisher's Exact test and Kruskal-Wallis test. RESULT The research result indicates that there is the significant difference between the enzymatic antioxidant serum contents of the catalase on the low born body weight babies and normal born weight babies with p value of 0.035 less then 0.05. The serum contents measurement of the catalase on the group of the low born body weight babies is 81.68±SD 15.22KU/L, whereas serum content measurement of the catalase on normal born weight babies is 92.02±SD 14.51KU/L. CONCLUSION The analysis result can be concluded that the mean of the catalase serum content on the low born body weight babies is lower than on normal born weight babies. It be concluded that the mean of the catalase serum content on the birth body weight babies is lower than on normal body weight babies. OBJECTIVES The purpose of this paper is to describe (1) the role of Toba Batak women in the praying performance of martonggotonggo and (2) the dancing performance of marpaniaran for the women's health at the Toba Batak traditional wedding ceremony. METHODS This paper reviewed using an anthropolinguistic approach with the analytic parameters is interconnection, valuability, and sustainability. The qualitative paradigm with ethnography model used in this study. RESULTS The praying performance of martonggotonggo expects the health for women and requires healthy women to support the performance at the Toba Batak traditional wedding ceremony. The dancing performance of marpaniaran show the women's health to dance well and long at the Toba Batak traditional wedding ceremony. CONCLUSION The roles of Toba Batak healthy women are required very much in the praying performance of martonggotonggo and the dancing performance of marpaniaran.