Occipitocervical fixation using bilateral C2 pedicle screws (C0-C2BiPS) and occipitocervical fixation using bilateral C2 translaminar screws (C0-C2BiLS) provide satisfactory stability. Bilateral fixation is not feasible for cases of C2 unilateral pedicle morphology abnormality and ipsilateral laminectomy. This study proposed and evaluated novel occipitocervical fixation using C2 unilateral pedicle screw and contralateral translaminar screws (C0-C2PSLS). In 6 human cadaveric specimens, an invitro experiment was performed with 2.0-Nm moment control in flexion-extension, lateral bending, and axial rotation to investigate biomechanical stability. Neutral zone and range of motion (ROM) between the occiput (C0) and C2 were measured in the intact state, after destabilization, and after sequential stabilization using C0-C2BiPS, C0-C2BiLS, and C0-C2PSLS constructs. Flexion-extension ROM of the intact specimens at C0-C2 was 27.4° ± 2.4°. Instrumentation with C0-C2PSLS, C0-C2BiPS, and C0-C2BiLS reduced flexion-extension ROM to 3.7° ± 1.3°, 4.7° ± 1.4°, and 4.5° ± 1.4°, respectively. In lateral bending, ROM values were 7.0° ± 0.6°, 4.5° ± 1.4°, 4.2° ± 1.4°, 2.7° ± 1.0°, respectively. In axial rotation, ROM values were 65.3° ± 5.7°, 2.5° ± 0.5°, 1.4° ± 0.5°, and 0.9° ± 0.6°, respectively. Comparing destabilized and intact specimens, all 3 constructs significantly reduced ROM and neutral zone values in flexion-extension, lateral bending, and axial rotation (P<0.05). Direct comparisons between the 3 constructs revealed no significant difference (P > 0.05). Novel C0-C2PSLS provides similar stabilization effect as C0-C2BiPS and C0-C2BiLS constructs and has potential for clinical use, especially for cases of C2 unilateral pedicle morphology abnormality and ipsilateral laminectomy. Novel C0-C2PSLS provides similar stabilization effect as C0-C2BiPS and C0-C2BiLS constructs and has potential for clinical use, especially for cases of C2 unilateral pedicle morphology abnormality and ipsilateral laminectomy. Studies on the surface roughness and color stainability of interim prostheses produced with 3-dimensional-printing technology are lacking. The purpose of this invitro study was to investigate the effect of different surface treatments on the surface roughness and stainability of 3-dimensionally printed, computer-aided design and computer-aided manufacturing (CAD-CAM) milled and conventional interim materials. A total of 320 specimens were fabricated from autopolymerizing polymethyl methacrylate, bis-acryl composite resin, CAD-CAM polymethyl methacrylate resin (milled), and 3-dimensionally printed composite resin (printed) (n=80). A group of each material was divided into 2 groups (n=40) as per the applied surface treatment procedure conventional polishing (C) or coated with a surface sealant (B). Surface roughness values were measured with a profilometer. Each group of specimens was then divided into 4 subgroups (n=10) and stored for 1 day, 7 days, and 30 days at 37 °C in different solutions distilled walant agent significantly decreased the staining of the materials. All tested materials had a surface roughness higher than the plaque accumulation threshold (0.2 μm). The surface roughness values of coated materials were significantly lower than those of their conventionally polished groups, except for the printed groups. The application of a surface sealant agent significantly decreased the staining of the materials.Protocols with static computer-aided implant placement provide more tangible clinical advantages than conventional implant placement methods. A technique to manufacture a dual-material implant surgical guide by using a vat-polymerization printer is described. The implant surgical guide combined a resilient intaglio and hard exterior surface. The technique should minimize the clinical adjustments needed to ensure fit and improve patient comfort. Established restorative protocols for patients after head and neck radiotherapy are lacking, increasing the failure rates of dental adhesive restorations. The purpose of this systematic review and meta-analysis was to analyze the evidence regarding the impact of head and neck radiotherapy on the longevity of dental adhesive restorations. A search was performed using PubMed, Scopus, and Embase in May 2018 (updated in November 2020). Data extraction was performed regarding the percentage of restoration failure among dental adhesive materials, including glass ionomer cements, resin-modified glass ionomer cements, and composite resins. Risk of bias was assessed by the meta-analysis of statistics assessment and review instrument (MAStARI). https://www.selleckchem.com/products/Amprenavir-(Agenerase).html Confidence in cumulative evidence was evaluated by the Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) protocol. Four studies met the inclusion criteria. All included studies were classified as having a moderate risk of bias and reported result for more randomized clinical trials regarding this subject. The results suggest that composite resin restorations associated with fluoride gel compliance seems to be the best alternative for restoring class V lesions in patients after head and neck radiotherapy. However, the results showed moderate certainty of evidence, which justifies the need for more randomized clinical trials regarding this subject. Limited information is available on the differences between tissue-level implants with an ultrathin threaded microsurface conical transmucosal portion and bone-level implants rehabilitated with conical custom abutments. The purpose of this retrospective study was to assess the outcomes of crowns designed as per the biologically oriented preparation technique (BOPT) cemented on conical titanium abutments on tissue-level and bone-level implants. Patients consecutively rehabilitated with a delayed loading protocol with anterior implant-supported single crowns with a feather-edge margin, in function for at least 4 years, were recruited and divided into 2 groups based on the implant type they had received tissue-level implants with a conical transmucosal portion or bone-level implants rehabilitated with a conical abutment by following the platform switching concept. Bone resorption, pink esthetic score (PES), and white esthetic score (WES) were collected and analyzed. The nonparametric Mann-Whitney test was performed to analyze all parameters (α=.