ies were deemed satisfactory when considering the locally advanced sarcoma disease status at primary diagnosis. Trial registration This study was registered at ClinicalTrials.gov Identifier NCT00790244 and with European Union Drug Regulating Authorities Clinical Trials No. EUDRACT 2007-001152-39. Preoperative chemotherapy and radiotherapy were associated with temporary wound-healing problems. Survival outcomes, local control and toxicities were deemed satisfactory when considering the locally advanced sarcoma disease status at primary diagnosis. Trial registration This study was registered at ClinicalTrials.gov Identifier NCT00790244 and with European Union Drug Regulating Authorities Clinical Trials No. EUDRACT 2007-001152-39.An amendment to this paper has been published and can be accessed via the original article. Despite evidence that thinness and muscularity are part of the female body ideal, there is not yet a reliable figure rating scale measuring the body image of women which includes both of these dimensions. To overcome this shortcoming, the Body Image Matrix of Thinness and Muscularity - Female Bodies (BIMTM-FB) was developed. The objective of this study is to analyze the psychometric properties of this measure. N = 607 non-clinical women and N = 32 women with eating disorders answered the BIMTM-FB as well as instruments assessing eating disorder symptoms and body image disturbance in order to test the convergent validity of the BIMTM-FB. To assess test-retest reliability, a two-week interval was determined. The results indicated that the body-fat dimension of the BIMTM-FB correlates significantly with the Contour Drawing Rating-Scale, the Drive for Leanness Scale (DLS) and the Body Appreciation Scale, while the muscularity dimension of the BIMTM-FB was significantly associated with the DLS and the Drive for Muscularity Scale, proving the convergent validity of the BIMTM-FB. High coefficients of test-retest reliability were found. Moreover, the BIMTM-FB differentiated between the clinical sample and the non-clinical controls. The BIMTM-FB is a figure rating scale assessing both thinness and muscularity as part of the female body ideal. Due to its high reliability and validity, the BIMTM-FB can be recommended in research and practice. The BIMTM-FB is a figure rating scale assessing both thinness and muscularity as part of the female body ideal. Due to its high reliability and validity, the BIMTM-FB can be recommended in research and practice. The Australia & New Zealand Academy for Eating Disorders (ANZAED) recently developed general principles and clinical practice standards recommended for mental health clinicians and dietitians providing treatment for people with eating disorders. Separate mental health practice and training standards were then devised as a foundation for strengthening the workforce and providing guidance to professional training programs and service providers on the minimal standards required for practice in the eating disorder field. The present recommendations for mental health professionals providing eating disorder treatment describe the following practice and training standards eating disorder treatment foundations (including co-ordination of services, establishing a positive therapeutic alliance, professional responsibility and knowledge of levels of care), assessment, diagnosis, intervention (including evidence-based intervention, managing psychiatric risk and managing co-morbid mental health problems), and monitoring and evaluation. Further work is required to disseminate these standards to clinicians providing services across Australia to people with eating disorders, and to support adherence in the clinic room where they can translate to improved outcomes for clients. Pathways to supporting adherence include expert supervision of practice, incorporation in training and supervised practice in university settings, and support with checklists that can be used by consumers and referring professionals. Further work is required to disseminate these standards to clinicians providing services across Australia to people with eating disorders, and to support adherence in the clinic room where they can translate to improved outcomes for clients. Pathways to supporting adherence include expert supervision of practice, incorporation in training and supervised practice in university settings, and support with checklists that can be used by consumers and referring professionals.An amendment to this paper has been published and can be accessed via the original article. A drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T cell mediated hypersensitivity reaction. Relapses of symptoms in the recovery phase are frequent and linked to the reduction of the corticosteroid treatment, to viral reactivations or to the exposure to new drugs. Here, we analyzed, how often the exposure to new drugs leads to new sensitization or drug-related relapses without detectable sensitization. 46 patients with DRESS treated in the allergy division of the Inselspital, Bern University Hospital, were retrospectively assessed. Drug-related relapses were analyzed in terms of frequency and whether a possible sensitization evaluated by skin tests and/or lymphocyte transformation tests (LTT) to the new drugs was detectable. Furthermore, drug tolerance was evaluated in a subset of patients. 56 relapses were observed in 27 of 46 patients with DRESS (58.7%). 33 (58.9%) of these relapses were associated with the use of new drugs, 30 drug-related relapses were evaluated by patch tt sensitized, drugs involved in drug related relapses could be reintroduced, if needed. Here, we propose a procedure for drug testing and future management of drug-related relapses in DRESS. Lockdown implemented to prevent the COVID-19 spread resulted in marked changes in the lifestyle. https://www.selleckchem.com/products/pifithrin-u.html The objective of the current study was to assess the impact of lockdown measures on a cohort of eating disorder (ED) patients being followed as part of an ongoing naturalistic treatment study. Ninety-nine patients aged 18 or older, currently or previously, in treatment at a Portuguese specialized hospital unit were contacted by phone and invited to participate in the current survey. Fifty-nine agreed to be interviewed by phone, and 43 agreed to respond to a set of self-report measures of ED symptoms, emotion regulation difficulties, clinical impairment, negative urgency, and COVID-19 impact, during the week after the end of the lockdown period. Data showed that of the 26 patients currently in treatment 8 remained unchanged (31%), 7 deteriorated (27%), and 11 reliably improved (42%). Of the 17 participants not currently in treatment 3 deteriorated (18%), 9 remained unchanged (53%), and 5 (29%) improved after the lockdown period.