To evaluate the evolution of river water quality in a changing environment, measuring the objective water quality is critical for understanding the rules of river water pollution. Based on the sample entropy theory and a nonlinear statistical method, this study aims to identify the spatiotemporal dynamics of water quality and its complexity in the Yangtze River basin using time series data, to separate the contributions of human activity and climate change to water quality, and to establish a data-driven risk assessment framework for the spatial (potential risk) and temporal (direct risk) aspects of water pollution. The results demonstrate that the spatiotemporal dynamics of water quality and sample entropy in each monitoring section are closely related to the characteristics of the corresponding location. The water quality of the main stream is superior, and its complexity is less than that of the tributaries. Cascade reservoir operation and vegetation status, agricultural production, and rainfall patterns exert great influences in the upper, middle, and lower reaches, respectively. Dam construction, urban agglomeration development, and interactions between river and lake are also influencing factors. An attributional analysis found that climate change and human activities negatively contributed to the evolution of NH3-N concentration in most of the monitored sections, and the average relative contribution rates of human activities to changes in water quality in the main and tributary streams were -55.46% and -48.49%, respectively. In addition, the construction of data-driven risk assessment framework can efficiently and accurately assess the potential and direct water pollution risks of rivers.Arsenic (As) and cadmium (Cd) are nonessential toxic metal(loids) that are carcinogenic to humans. Hence, reducing the bioavailability of these metal(loids) in soils and decreasing their accumulation in rice grains is essential for agroecology, food safety, and human health. https://www.selleckchem.com/peptide/adh-1.html Iron (Fe)-enriched corncob biochar (FCB), Fe-enriched charred eggshell (FEB), and Fe-enriched corncob-eggshell biochar (FCEB) were prepared for soil amelioration. The amendment materials were applied at 1% and 2% application rates to observe their alleviation effects on As and Cd loads in rice paddy tissues and yield improvements using pot trials. The FCEB treatment increased paddy yields compared to those of FCB (9-12%) and FEB (3-36%); this could be because it contains more plant essential nutrients than FCB and a lower calcite content than that of FEB. In addition, FCEB significantly reduced brown rice As (AsBR, 29-60%) and Cd (CdBR, 57-81%) contents compared to those of the untreated control (CON). At a 2% application rate, FCEB reduced the average mobility of As (56%) and Cd (62%) in rhizosphere porewater and enhanced root Fe-plaque formation (76%) compared to those of CON. Moreover, the enhanced Fe-plaque sequestered a substantial amount of As (171.4%) and Cd (90.8%) in the 2% FCEB amendment compared to that of CON. Pearson correlation coefficients and regression analysis indicated that two key mechanisms likely control AsBR and CdBR accumulations. First, rhizosphere soil pH and Eh controlled As and Cd availabilities in porewaters and their speciation in the soil. Second, greater Fe-plaque formation in paddy roots grown in the amended soils provided a barrier for plant uptake of the metal(loids). These observations demonstrate that soil amendment with Fe-enriched corncob-eggshell biochar (e.g., 2% FCEB) is a prospective approach for the remediation of metal accumulation from the soil to grain system while simultaneously increasing paddy yield. Numerous epidemiological studies have investigated the effects of short-term and long-term exposure to ambient air pollution on hypertension and blood pressure among children and adolescents. However, the results were controversial. To provide researchers reliable evidence, this meta-analysis was performed. We searched all published studies in four databases examining the effects of particulate matter (PM , PM and PM ), nitrogen oxide (NO ), sulfur dioxide (SO ), ozone (O ) and carbon monoxide (CO) on hypertension and blood pressure in children and adolescents. Overall risk estimates associated with per 10 μg/m increase of air pollution were analyzed by a random-effect model for articles with significant heterogeneity, otherwise, a fixed-effect model was applied. Subgroup analysis was conducted for studies with significant heterogeneity. Of 3918 identified literatures, 154 were evaluated in-depth with 15 satisfying inclusion criteria. Increased risk of hypertension was associated with long-termiated with higher hypertension prevalence and elevated blood pressure in children and adolescents.Micrococcus luteus SA211, isolated from the Salar del Hombre Muerto in Argentina, developed responses that allowed its survival and growth in presence of high concentrations of lithium chloride (LiCl). In this research, analysis of total genome sequencing and a comparative proteomic approach were performed to investigate the responses of this bacterium to the presence of Li. Through proteomic analysis, we found differentially synthesized proteins in growth media without LiCl (DM) and with 10 (D10) and 30 g/L LiCl (D30). Bi-dimensional separation of total protein extracts allowed the identification of 17 over-synthesized spots when growth occurred in D30, five in D10, and six in both media with added LiCl. The results obtained showed different metabolic pathways involved in the ability of M. luteus SA211 to interact with Li. These pathways include defense against oxidative stress, pigment and protein synthesis, energy production, and osmolytes biosynthesis and uptake. Furthermore, mono-dimensional gel electrophoresis revealed differential protein synthesis at equivalent NaCl and LiCl concentrations, suggesting that this strain would be able to develop different responses depending on the nature of the ion. Moreover, the percentage of proteins with acidic pI predicted and observed was highlighted, indicating an adaptation to saline environments. To the best of our knowledge, this is the first report showing the relationship between protein synthesis and genome sequence analysis in response to Li, showing the great biotechnological potential that native microorganisms present, especially those isolated from extreme environments.