In addition, we performed KEGG pathway and GO term enrichment analysis, and the results indicated that the cancer drivers predicted by frDriver were related to processes such as cancer formation and gene regulation.The performance of motor imagery (MI) based Brain-computer interfacing (BCI) is easily affected by noise and redundant information that exists in the multi-channel electroencephalogram (EEG). To solve this problem, many temporal and spatial feature based channel selection methods have been proposed. However, temporal and spatial features do not accurately reflect changes in the power of the oscillatory EEG. Thus, spectral features of MI-related EEG signals may be useful for channel selection. Bispectrum analysis is a technique developed for extracting non-linear and non-Gaussian information from non-linear and non-Gaussian signals. The features extracted from bispectrum analysis can provide frequency domain information about the EEG. Therefore, in this study, we propose a bispectrum-based channel selection (BCS) method for MI-based BCI. The proposed method uses the sum of logarithmic amplitudes (SLA) and the first order spectral moment (FOSM) features extracted from bispectrum analysis to select EEG channels without redundant information. Three public BCI competition datasets (BCI competition IV dataset 1, BCI competition III dataset IVa and BCI competition III dataset IIIa) were used to validate the effectiveness of our proposed method. The results indicate that our BCS method outperforms use of all channels (83.8% vs 69.4%, 86.3% vs 82.9% and 77.8% vs 68.2%, respectively). Furthermore, compared to the other state-of-the-art methods, our BCS method also can achieve significantly better classification accuracies for MI-based BCI (Wilcoxon signed test, p less then 0.05).Data movement, particularly access to the main memory, has been the bottleneck of most computing problems. Ray tracing is no exception. We propose an unconventional solution that combines a ray ordering scheme that minimizes access to the scene data with a large on-chip buffer acting as near-compute storage that is spread over multiple chips. We demonstrate the effectiveness of our approach by introducing ****-RT (MAny CHip - Ray Tracing), a new hardware architecture for accelerating ray tracing. Extending the concept of dual streaming, we optimize the main memory accesses to a level that allows the same memory system to service multiple processor chips at the same time. While a multiple chip solution might seem to imply increased energy consumption as well, because of the reduced memory traffic we are able to demonstrate, performance increases while maintaining reasonable energy usage compared to academic and commercial architectures. This paper extends our previous work [1] with design space exploration of the L3 cache size, more detailed evaluation of energy and memory performance, a discussion of energy delay product, and a brief exploration of boards with 16 chips. We also introduce new treelet enqueueing logic for the predictive scheduler.We present 3D virtual pancreatography (VP), a novel visualization procedure and application for non-invasive diagnosis and classification of pancreatic lesions, the precursors of pancreatic cancer. https://www.selleckchem.com/products/bb-94.html Currently, non-invasive screening of patients is performed through visual inspection of 2D axis-aligned CT images, though the relevant features are often not clearly visible nor automatically detected. VP is an end-to-end visual diagnosis system that includes a machine learning based automatic segmentation of the pancreatic gland and the lesions, a semi-automatic approach to extract the primary pancreatic duct, a machine learning based automatic classification of lesions into four prominent types, and specialized 3D and 2D exploratory visualizations of the pancreas, lesions and surrounding anatomy. We combine volume rendering with pancreas- and lesion-centric visualizations and measurements for effective diagnosis. We designed VP through close collaboration and feedback from expert radiologists, and evaluated it on multiple real-world CT datasets with various pancreatic lesions and case studies examined by the expert radiologists.Rectilinear face recognition models suffer from severe performance degradation when applied to fisheye images captured by 360° ****-to-**** dual fisheye cameras. We propose a novel face rectification method to combat the effect of fisheye image distortion on face recognition. The method consists of a classification network and a restoration network specifically designed to handle the non-linear property of fisheye projection. The classification network classifies an input fisheye image according to its distortion level. The restoration network takes a distorted image as input and restores the rectilinear geometric structure of the face. The performance of the proposed method is tested on an end-to-end face recognition system constructed by integrating the proposed rectification method with a conventional rectilinear face recognition system. The face verification accuracy of the integrated system is 99.18% when tested on images in the synthetic Labeled Faces in the Wild (LFW) dataset and 95.70% for images in a real image dataset, resulting in an average accuracy improvement of 6.57% over the conventional face recognition system. For face identification, the average improvement over the conventional face recognition system is 4.51%.Handling deformation is one of the biggest challenges associated with point cloud registration. When deformation happens due to the motion of an animated object which actively changes its location and general shape, registration of two instances of the same object turns out to be a challenging task. The focus of this work is to address the problem by leveraging the complementary attributes of local and global geometric structures of the point clouds. We define an energy function which consists of local and global terms, as well as a semi-local term to model the intermediate level geometry of the point cloud. The local energy estimates the transformation parameters at the lowest level by assuming a reduced deformation model. The parameters are estimated in a closed form solution, which are then used to assign the initial probability of a stochastic model working at the intermediate level. The global energy term estimates the overall transformation parameters by minimizing a nonlinear least square function via Gauss-Newton optimization framework.
In addition, we performed KEGG pathway and GO term enrichment analysis, and the results indicated that the cancer drivers predicted by frDriver were related to processes such as cancer formation and gene regulation.The performance of motor imagery (MI) based Brain-computer interfacing (BCI) is easily affected by noise and redundant information that exists in the multi-channel electroencephalogram (EEG). To solve this problem, many temporal and spatial feature based channel selection methods have been proposed. However, temporal and spatial features do not accurately reflect changes in the power of the oscillatory EEG. Thus, spectral features of MI-related EEG signals may be useful for channel selection. Bispectrum analysis is a technique developed for extracting non-linear and non-Gaussian information from non-linear and non-Gaussian signals. The features extracted from bispectrum analysis can provide frequency domain information about the EEG. Therefore, in this study, we propose a bispectrum-based channel selection (BCS) method for MI-based BCI. The proposed method uses the sum of logarithmic amplitudes (SLA) and the first order spectral moment (FOSM) features extracted from bispectrum analysis to select EEG channels without redundant information. Three public BCI competition datasets (BCI competition IV dataset 1, BCI competition III dataset IVa and BCI competition III dataset IIIa) were used to validate the effectiveness of our proposed method. The results indicate that our BCS method outperforms use of all channels (83.8% vs 69.4%, 86.3% vs 82.9% and 77.8% vs 68.2%, respectively). Furthermore, compared to the other state-of-the-art methods, our BCS method also can achieve significantly better classification accuracies for MI-based BCI (Wilcoxon signed test, p less then 0.05).Data movement, particularly access to the main memory, has been the bottleneck of most computing problems. Ray tracing is no exception. We propose an unconventional solution that combines a ray ordering scheme that minimizes access to the scene data with a large on-chip buffer acting as near-compute storage that is spread over multiple chips. We demonstrate the effectiveness of our approach by introducing Mach-RT (MAny CHip - Ray Tracing), a new hardware architecture for accelerating ray tracing. Extending the concept of dual streaming, we optimize the main memory accesses to a level that allows the same memory system to service multiple processor chips at the same time. While a multiple chip solution might seem to imply increased energy consumption as well, because of the reduced memory traffic we are able to demonstrate, performance increases while maintaining reasonable energy usage compared to academic and commercial architectures. This paper extends our previous work [1] with design space exploration of the L3 cache size, more detailed evaluation of energy and memory performance, a discussion of energy delay product, and a brief exploration of boards with 16 chips. We also introduce new treelet enqueueing logic for the predictive scheduler.We present 3D virtual pancreatography (VP), a novel visualization procedure and application for non-invasive diagnosis and classification of pancreatic lesions, the precursors of pancreatic cancer. https://www.selleckchem.com/products/bb-94.html Currently, non-invasive screening of patients is performed through visual inspection of 2D axis-aligned CT images, though the relevant features are often not clearly visible nor automatically detected. VP is an end-to-end visual diagnosis system that includes a machine learning based automatic segmentation of the pancreatic gland and the lesions, a semi-automatic approach to extract the primary pancreatic duct, a machine learning based automatic classification of lesions into four prominent types, and specialized 3D and 2D exploratory visualizations of the pancreas, lesions and surrounding anatomy. We combine volume rendering with pancreas- and lesion-centric visualizations and measurements for effective diagnosis. We designed VP through close collaboration and feedback from expert radiologists, and evaluated it on multiple real-world CT datasets with various pancreatic lesions and case studies examined by the expert radiologists.Rectilinear face recognition models suffer from severe performance degradation when applied to fisheye images captured by 360° back-to-back dual fisheye cameras. We propose a novel face rectification method to combat the effect of fisheye image distortion on face recognition. The method consists of a classification network and a restoration network specifically designed to handle the non-linear property of fisheye projection. The classification network classifies an input fisheye image according to its distortion level. The restoration network takes a distorted image as input and restores the rectilinear geometric structure of the face. The performance of the proposed method is tested on an end-to-end face recognition system constructed by integrating the proposed rectification method with a conventional rectilinear face recognition system. The face verification accuracy of the integrated system is 99.18% when tested on images in the synthetic Labeled Faces in the Wild (LFW) dataset and 95.70% for images in a real image dataset, resulting in an average accuracy improvement of 6.57% over the conventional face recognition system. For face identification, the average improvement over the conventional face recognition system is 4.51%.Handling deformation is one of the biggest challenges associated with point cloud registration. When deformation happens due to the motion of an animated object which actively changes its location and general shape, registration of two instances of the same object turns out to be a challenging task. The focus of this work is to address the problem by leveraging the complementary attributes of local and global geometric structures of the point clouds. We define an energy function which consists of local and global terms, as well as a semi-local term to model the intermediate level geometry of the point cloud. The local energy estimates the transformation parameters at the lowest level by assuming a reduced deformation model. The parameters are estimated in a closed form solution, which are then used to assign the initial probability of a stochastic model working at the intermediate level. The global energy term estimates the overall transformation parameters by minimizing a nonlinear least square function via Gauss-Newton optimization framework.
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