A variety of factors affect the success of music therapy students in practica. Many music therapy students may have invisible illnesses or invisible disabilities (II/ID) that affect their work. II/ID have physical or psychological effects but are not apparent to an observer. Such illnesses may include chronic illnesses, mental illnesses, and developmental disabilities. Although researchers have studied the success of post-secondary students with II/ID and the success of music therapy students without II/ID, there is a lack of research on music therapy students who identify with having II/ID. This researcher used an exploratory online survey to investigate the prevalence of II/ID among music therapy students and how it may affect their success in music therapy practica. Quantitative responses were compiled and analyzed into frequencies and percentages, and open-ended responses were coded and analyzed for patterns and themes. Results indicated that music therapy students with II/ID have various reasons for disclosure or nondisclosure. Some music therapy students with II/ID required accommodations, while many did not. Additionally, the effects of II/ID on music therapy practica students included physical, psychosocial, and cognitive symptoms, which led to various choices for disclosure/nondisclosure and the request/use of individualized accommodations. Music therapy students with II/ID self-reported that making decisions regarding appropriate disclosure and determining their need for accommodations or not allowed them to be more successful in practica. © The Author(s) 2020. Published by Oxford University Press on behalf of American Music Therapy Association. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.PURPOSE The purpose of this study was to quantify the prevalence of impostor phenomenon (IP) and to assess well-being in pharmacy residents, as well as analyze the effects of demographics on these outcomes. METHODS A cross-sectional, survey-based study was performed. Pharmacy residency program directors and pharmacy directors were asked to forward an invitation email to actively enrolled postgraduate year 1 (PGY1) and postgraduate year 2 pharmacy residents in March 2019. The survey used the Clance Impostor Phenomenon Scale (CIPS) to identify IP and the Mayo Clinic Resident/Fellow Well-Being Index (RWBI) to assess resident well-being. RESULTS Survey respondents were mostly female, enrolled in PGY1 programs and single with no children. Of the 720 responses included in the study, 57.5% (n = 414) were identified as "impostors" (CIPS score of ≥62), with a mean CIPS score of 64.0 (SD, 15.0). Prior mental health treatment and increased hours worked per week were significant predictors of IP. The greatest correlation was found in those working greater than 80 hours per week compared to less than 60 hours per week (ß = 9.845; P less then 0.001). The mean RWBI score was 4.2 (SD, 1.8), with 47.8% (n = 344) of residents scoring ≥5, the cutoff for identifying those at greatest risk of distress. Age, previous mental health treatment, and increasing hours worked per week were significant predictors of RWBI ≥5. CIPS and RWBI scores were found to exhibit weak but significant correlation (ρ = 0.357; P less then 0.001). CONCLUSION Pharmacy residents displayed significantly higher prevalence of IP vs comparable groups as well as significantly more distress with potential for a personal and/or professional consequence. © American Society of Health-System Pharmacists 2020. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.BACKGROUND Pain is one of the main symptoms associated with spinal cord injury and may be associated with changes to the central nervous system. PURPOSE This article provides an overview of the evidence relating to central nervous system changes (CNS) (structural and functional) associated with pain in spinal cord injuries (SCI).Data sources. A systematic review was performed, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, on PubMed, EMBASE, and Web of Science in March 2018. STUDY SELECTION Studies were selected if study changes in CNS of patients with SCI regardless of the type of imagery. DATA EXTRACTION Data were extracted by two blinded reviewers. DATA SYNTHESIS There is moderate evidence for impaired electroencephalographic function and metabolic abnormalities in the anterior cingulate in patients experiencing pain. There is preliminary evidence that patients with pain have morphological and functional changes to the somatosensory cortex and alterations to thalamic metabolism. There are conflicting data regarding the relationships between lesion characteristics and pain. In contrast, patients without pain may display protective neuroplasticity. LIMITATIONS AND CONCLUSION Further studies are required to elucidate fully the relationships between pain and neuroplasticity in patients with spinal cord injuries. However, current evidence may support the use of physical therapist treatments targeting central nervous system plasticity in patients with spinal cord injury pain. © 2020 American Physical Therapy Association.We report a COVID-19 family cluster caused by a presymptomatic case. There were 9 family members, including 8 laboratory-confirmed with COVID-19, and a 6-year-old child had no evidence of infection. Amongst the 8 patients, one adult and one 13-month-old infant were asymptomatic, one adult was diagnosed as having severe pneumonia. © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.In eukaryotic cells, with the exception of the specialized genomes of mitochondria and plastids, all genetic information is sequestered within the nucleus. This arrangement imposes constraints on how the information can be tailored for different cellular regions, particularly in cells with complex morphologies like neurons. Although messenger RNAs (mRNAs), and the proteins that they encode, can be differentially sorted between cellular regions, the information itself does not change. RNA editing by adenosine deamination can alter the genome's blueprint by recoding mRNAs; however, this process too is thought to be restricted to the nucleus. In this work, we show that ADAR2 (adenosine deaminase that acts on RNA), an RNA editing enzyme, is expressed outside of the nucleus in squid neurons. Furthermore, purified axoplasm exhibits adenosine-to-inosine activity and can specifically edit adenosines in a known substrate. https://www.selleckchem.com/products/msdc-0160.html Finally, a transcriptome-wide analysis of RNA editing reveals that tens of thousands of editing sites (>70% of all sites) are edited more extensively in the squid giant axon than in its cell bodies.