The practical work described here is designed for third-year bachelor students in Life Sciences attending a kidney physiology course. It illustrates how urinary biochemistry can be used for a medical diagnosis. Students have to measure glucose, proteins, and creatinine concentrations in three simulated urine samples. First, they independently elaborate detailed protocols from the biochemical kit's technical sheets. Second, after correction of the protocols by the teacher, they perform the biochemical assays. Finally, students write a report in which they interpret the biochemical data and use them in the context of histological images assigned to each urine sample. With their results, their theoretical background and scientific articles supplied by the teacher, they establish the diagnosis indicating which patients are diseased and from which disease they are suffering (diabetes without nephropathy, diabetic nephropathy or hypertensive nephropathy). The originality of this practical work is to give student autonomy from the start of the project by requiring them to write the protocols, and determine the diagnosis by themselves. Simple and inexpensive, this practical forces students to mobilize their knowledge in renal physiology and pathophysiology as well as those acquired in other disciplines such as biochemistry or cellular biology. A survey conducted on two classes of students confirmed that this type of training helps students to better understand renal physiology, to realize the importance of interdisciplinarity (biochemistry, histology, and physiology) and to develop confidence in their ability to work independently.In this work, a facile aqueous synthesis strategy was used (complete in 5 min at room temperature) to produce large-size Pd, PdCu, and PdPtCu nanomeshes without additional organic ligands or solvent and the volume restriction of reaction solution. The obtained metallic nanomeshes possess graphene-like morphology and a large size of dozens of microns. Abundant edges (coordinatively unsaturated sites, steps, and corners), defects (twins), and mesopores are seen in the metallic ultrathin structures. The formation mechanism for porous Pd nanomeshes disclosed that they undergo oriented attachment growth along the ⟨111⟩ direction. Owing to structural and compositional advantages, PdCu porous nanomeshes with certain elemental ratios (e. g., Pd87 Cu13 ) presented enhanced electrocatalytic performance (larger mass activity, better CO tolerance and stability) toward ethanol oxidation.Infertility can be devastating for some couples. The purpose of this paper is to demonstrate a translation of knowledge and nursing theory-based practice regarding nursing care of couples experiencing infertility through a case study approach. It is important to consider the translation of knowledge to probable scenarios so that we may have opportunities to be better prepared when addressing such situations in actual nursing practice. Data sources include current literature, theoretical perspectives on power as knowing participation in change and nursing classifications. https://www.selleckchem.com/products/ionomycin.html Data synthesis is illustrated within the context of a simulated case study of a couple experiencing unexplained secondary infertility through the application of a theory-based practice methodology, health patterning. The authors conclude that the theoretical perspectives of unitary science and the theory of power as knowing participation in change can be applied in practice. Theory-based practice methodologies such as health patterning offer an opportunity to provide holistic care to couples experiencing infertility. Using these theoretical perspectives, nurses can engage with couples expressing a readiness for enhanced power for a desired change. Nursing implications include the value of theory-based practice and the essential view of couples as unique human beings. In addition, it demonstrates the ongoing usefulness of case study approaches for nursing education as vehicles to enhance awareness of unitary experiences, updates to clinical care, and demonstration of the application of theory to practice. Regional metastasis of head and neck cutaneous squamous cell carcinoma (HNcSCC) can be seen in either parotid and/or cervical lymph nodes. The aim of this study was to assess whether there was a difference in prognosis between parotid and cervical nodal metastases. Patients with regional metastasis from HNcSCC were identified from an institutional database. Disease-specific (DSS) and overall survival (OS) were calculated using the Kaplan-Meier method and Cox proportional hazards models. Five hundred and thirty-five patients were identified with median follow-up of 26.4months (3-255 months). Two hundred and thirty-five patients had parotid metastasis, 96 patients had neck metastasis, and 204 patients had both. On multivariable analysis, any regional metastasis to the neck when compared to parotid alone conferred worse DSS (HR 1.8, p=0.007) and OS (HR 1.3, p=0.024). Regional metastasis of HNcSCC to the neck confers worse outcomes compared to metastasis to the parotid alone. Regional metastasis of HNcSCC to the neck confers worse outcomes compared to metastasis to the parotid alone.Recent studies have shown that dynamic nuclear polarization (DNP) can be used to detect 17 O solid-state NMR spectra of naturally abundant samples within a reasonable experimental time. Observations using indirect DNP, which relies on 1 H mediation in transferring electron hyperpolarization to 17 O, are currently limited mostly to hydroxyls. Direct DNP schemes can hyperpolarize non-protonated oxygen near the radicals; however, they generally offer much lower signal enhancements. In this study, we demonstrate the detection of signals from non-protonated 17 O in materials containing silicon. The sensitivity boost that made the experiment possible originates from three sources indirect DNP excitation of 29 Si via protons, indirect detection of 17 O through 29 Si nuclei using two-dimensional 29 Si17 O D-HMQC, and Carr-Purcell-Meiboom-Gill refocusing of 29 Si magnetization during acquisition. This 29 Si-detected scheme enabled, for the first time, 2D 17 O-29 Si heteronuclear correlation spectroscopy in mesoporous silica and silica-alumina surfaces at natural abundance.