Specifically, SPLH first maps the independent discrete label vectors and binary hash codes into a linkage space, through which the relative semantic distance between data points can be assessed precisely. As a result, the pairwise similarities within the newly arriving data stream are exploited to learn the latent semantic space to benefit binary code learning. To learn the model parameters effectively, we further propose an alternating optimization algorithm. Extensive experiments conducted on three widely-used datasets demonstrate the superior performance of SPLH over several state-of-the-art online hashing methods.Image alignment/registration/correspondence is a critical prerequisite for many vision-based tasks, and it has been widely studied in computer vision. However, aligning images from different domains, such as cross-weather/season road scenes, remains a challenging problem. Inspired by the success of classic intensity-constancy-based image alignment methods and the modern generative adversarial network (GAN) technology, we propose a cross-weather road scene alignment method called latent generative model with intensity constancy. From a novel perspective, the alignment problem is formulated as a constrained 2D flow optimization problem with latent encoding, which can be decoded into an intensity-constancy image on the latent image manifold. The manifold is parameterized by a pre-trained GAN, which is able to capture statistic characteristics from large datasets. Moreover, we employ the learned manifold to constrain the warped latent image identical to the target image, thereby producing a realistic warping effect. Experimental results on several cross-weather/season road scene datasets demonstrate that our approach can significantly outperform the state-of-the-art methods.Shear-wave elastography (SWE) permits local estimation of tissue elasticity, an important imaging marker in biomedicine. This recently-developed, advanced technique assesses the speed of a laterally-travelling shear wave after an acoustic radiation force "push" to estimate local Young's moduli in an operator-independent fashion. In this work, we show how synthetic SWE (sSWE) images can be generated based on conventional B-mode imaging through deep learning. Using sideby-side-view B-mode/SWE images collected in 50 patients with prostate cancer, we show that sSWE images with a pixel-wise mean absolute error of 4.5±0.96 kPa with regard to the original SWE can be generated. Visualization of high-level feature levels through t-Distributed Stochastic Neighbor Embedding reveals substantial overlap between data from two different scanners. Qualitatively, we examined the use of the sSWE methodology for B-mode images obtained with a scanner without SWE functionality. We also examined the use of this type of network in elasticity imaging in the thyroid. Limitations of the technique reside in the fact that networks have to be retrained for different organs, and that the method requires standardization of the imaging settings and procedure. Future research will be aimed at development of sSWE as an elasticity-related tissue typing strategy that is solely based on B-mode ultrasound acquisition, and the examination of its clinical utility.Photon-counting spectral computed tomography (CT) is capable of material characterization and can improve diagnostic performance over traditional clinical CT. However, it suffers from photon count starving for each individual energy channel which may cause severe artifacts in the reconstructed images. Furthermore, since the images in different energy channels describe the same object, there are high correlations among different channels. To make full use of the inter-channel correlations and minimize the count starving effect while maintaining clinically meaningful texture information, this paper combines a region-specific texture model with a low-rank correlation descriptor as an a priori regularization to explore a superior texture preserving Bayesian reconstruction of spectral CT. Specifically, the inter-channel correlations are characterized by the low-rank representation, and the inner-channel regional textures are modeled by a texture preserving Markov random field. In other words, this paper integrates the spectral and spatial information into a unified Bayesian reconstruction framework. The widely-used Split-Bregman algorithm is employed to minimize the objective function because of the non-differentiable property of the low-rank representation. To evaluate the tissue texture preserving performance of the proposed method for each channel, three references are built for comparison one is the traditional CT image from energy integration detection. The second one is spectral images from dual-energy CT. The third one is individual channels images from custom-made photon-counting spectral CT. As expected, the proposed method produced promising results in terms of not only preserving texture features but also suppressing image noise in each channel, comparing to existing methods of total variation (TV), low-rank TV and tensor dictionary learning, by both visual inspection and quantitative indexes of root mean square error, peak signal to noise ratio, structural similarity and feature similarity.Quantitative photoacoustic tomography aims at estimating optical parameters from photoacoustic images that are formed utilizing the photoacoustic effect caused by the absorption of an externally introduced light pulse. This optical parameter estimation is an ill-posed inverse problem, and thus it is sensitive to measurement and modeling errors. In this work, we propose a novel way to solve the inverse problem of quantitative photoacoustic tomography based on the perturbation Monte Carlo method. Monte Carlo method for light propagation is a stochastic approach for simulating photon trajectories in a medium with scattering particles. It is widely accepted as an accurate method to simulate light propagation in tissues. https://www.selleckchem.com/products/jph203.html Furthermore, it is numerically robust and easy to implement. Perturbation Monte Carlo maintains this robustness and enables forming gradients for the solution of the inverse problem. We validate the method and apply it in the framework of Bayesian inverse problems. The simulations show that the perturbation Monte Carlo method can be used to estimate spatial distributions of both absorption and scattering parameters simultaneously.