Calcium pectinate (CaP) gel is traditionally prepared by de-esterifying high methoxyl pectin (HMP) to low methoxyl pectin (LMP), followed by gelation with calcium. To save both time and cost in the production of CaP gel, an alternative method was developed by the addition of CaCl to HMP at alkaline pH. To optimize the production, response surface methodology (RSM) was used to investigate the effects of temperature (30-50 °C), time (20-40 min) and pH (8-10) on yield, calcium content of the CaP gel and the degree of esterification (DE) of pectin following decalcification of CaP (DC-pectin). The linear term for pH had a significant effect (P < 0.01) on all three responses, whereas interaction effects were not significant (P > 0.01), except on the calcium content (P < 0.01). The optimized process conditions (temperature, time and pH) to obtain maximum CaP-HMP gel yield (88.83%) were 50 °C, 40 min and pH 9.6, and for the highest calcium content (97.23 mg g ) they were 40 °C, 30 min and pH 9.7. DC-pectin was a typical LMP with DE varying from 26.92% to 50.33%. The DE of DC-pectin could be predicted by a model that proved significant (R =0.9888). The optimum conditions were established to produce CaP gels from HMP with high yield and calcium content. Also, LMP with predictable DE can be produced following a significant model. This study provides new insights into the production and application of CaP gel. © 2021 Society of Chemical Industry. The optimum conditions were established to produce CaP gels from HMP with high yield and calcium content. Also, LMP with predictable DE can be produced following a significant model. This study provides new insights into the production and application of CaP gel. © 2021 Society of Chemical Industry.In this study, a new fluorinated methacrylamide (MACF) was synthesized and evaluated as an adsorbent in the dispersive solid-phase extraction for the effective determination and extraction of 20 organophosphorus pesticides (OPPs) from ginseng samples using the QuEChERS (quick, easy, cheap, effective, rugged, safe) method coupled with GC-MS/MS. The properties of MACF were characterized using Fourier-transform infrared spectroscopy, elemental analysis, and high-resolution 19 F NMR. MACF, chitosan, primary and secondary amine, octadecylsilane, graphitized carbon black, Z-Sep, Z-Sep+ , and EMR-Lipid were compared in terms of extraction efficiency. The best results were obtained when MACF was used. Matrix-matched calibration was employed for quantification. All the OPPs exhibited good linearity (r2  > 0.9969) with the concentration at their respective concentration ranges. The limits of detection were 1.5-3.0 μg/kg, and the limits of quantification were 5.0-10.0 μg/kg. The trueness of the 20 pesticides at four spiked levels ranged from 86.1 to 111.1%, and the relative standard deviation was less than 11.3%. The modified QuEChERS method using MACF as the adsorbent was sensitive, reliable, and cost-effective and could be used for the determination of 20 OPP residues in ginseng.Magnetic flux measurements of toners can aid in the rapid differentiation of toner-printed specimens in the context of investigations of forgeries or alterations of printed documents. However, some variables that may impact magnetic flux measurements, including hysteresis effects, are not currently well understood. This study assessed the impact of hysteresis and other induction spatial effects on magnetic flux measurements of toners analyzing five toner-printed samples produced from different devices. The samples were printed with controlled grids of square, rectangular, and elongated rectangular blocks with the same area. Thirty measurements were conducted on each sample, on each grid type. The measurements were repeated in planes of rotation 90°, 180°, and 270° counter to this original position. The values obtained for the square grids were evaluated using one-way ANOVA to assess the presence and impact of hysteresis effects. The values obtained for the rectangular grids were compared with those obtained for the square grids using a two-way ANOVA to determine potential induction current orientation effects. The results of both one-way and two-way ANOVA were significant with p less then 0.05, indicating that both hysteresis effects and induction current spatial effects contribute significantly to variations in magnetic flux measurements. Results confirmed that sensor orientation is an important factor that must be accounted for in method protocols for the measurement of magnetic flux of toners. Controlling these variables is a step forward toward the development of a reliable screening method to be deployed in the context of investigations of document forgeries or alterations. This study aimed to establish the Turkish validity and reliability of the Kiersma-Chen empathy scale (KCES) and determine its psychometric properties. This methodological study was carried out with 227 nursing students between April and May 2019. The Cronbach's alpha coefficient of the total scale is 0.854, the test-retest coefficient was high for the total scale (r = 0.989), and total-item correlations ranged between 0.398 and 0.712. The KCES-TR is a valid and reliable scale to measure empathy in nursing students. The KCES-TR is a valid and reliable scale to measure empathy in nursing students.Based on FLUKA, the present study is aimed at calculating the microdosimetric distributions of electron beams (6, 12 and 18 MeV) for radiotherapy as a function of depth in water at a site-size of 1 μm using a tissue-equivalent proportional counter (TEPC). Using the calculated microdosimetric distributions, the depth-specific relative biological effectiveness (RBE) of electron beams used in radiotherapy is calculated based on the theory of dual radiation action (TDRA) and the microdosimetric kinetic model (MKM). https://www.selleckchem.com/products/bms-986205.html The TDRA-based calculation shows the variation of RBE of an electron beam with the absorbed dose and depth in water. In this study, we compared the RBE values calculated based on the TDRA and MKM. The FLUKA-based microdosimetric distributions in water obtained using the pre-calculated electron fluence spectra resulted in an improvement in the computational efficiency by a factor of 110 when compared with a full simulation. Depending on the beam energy and depth of water, RBETDRA was in the range 0.67-0.