annualreviews.org/page/journal/pubdates for revised estimates.Purpose To study the complication rate of NdYAG laser posterior capsulotomy in patients with uveitis.Method Retrospective case note analysis of pseudophakic uveitis patients having undergone NdYAG laser posterior capsulotomy between January 2016 and December 2018. Complications documented included uveitis flare, raised intraocular pressure, intraocular lens damage/displacement, cystoid macular edema, and retinal detachment.Results There were 39 eyes of 38 patients (20M, 18F; age 27-89 years). Mean interval between cataract surgery and laser was 55 months (range 8-286 months). Mean laser energy was 79 mJ (range 33-207 mJ). At 3 months 62% of eyes achieved a 2-5 Snellen line improvement that was maintained at 12 months. Vision was unchanged in 21% of eyes due to preexisting pathology, with no eyes having worse vision. No post-laser complications were documented.Conclusions NdYAG laser posterior capsulotomy is a safe procedure in uveitis patients, resulting in a good improvement in vision.Background Lung cancer is the leading cause of cancer-related death worldwide, imposing an enormous economic burden on society. Several studies have identified a link between the genetic polymorphisms in vitamin D pathways and lung cancer risk; however, the results remain inconclusive. The aim of this study was to estimate the effect of polymorphisms in the vitamin D receptor (VDR) and GC genes on lung cancer risk. Methods Eligible case-control studies published between January 2000 and December 2018 were searched and studied. The pooled odds ratio and its 95% confidence interval were used to estimate the effect. Results Fifteen articles that included 4732 lung cancer patients and 4337 controls were identified for this study. Our results demonstrated that the VDR Bsm1 polymorphism (p less then 0.05) and the TC and TT+TC genotypes of the Cdx2 polymorphism (p less then 0.05) were protective factors for avoiding lung cancer incidence, while T allele and TT genotype of Taq1 polymorphism (p less then 0.05) wpulations. Future case-control studies with different ethnicities are still needed to generalize these associations.PURPOSE There are strategies to bring quality cancer care to underserved patients, but poor use of the principles of teamwork is a major barrier to achieving quality services. The intent of this study was to assess teamwork as perceived by health care workers caring for patients with cancer. METHODS We conducted a survey among health care professionals in cancer care at 3 tertiary centers in southwestern Nigeria from July to November 2016. Respondents rated teamwork using the Safety Attitudes Questionnaire; we focused on the teamwork climate subscale comparing health care providers and institutions using analysis of variance and on collaboration using logistic regression. RESULTS Three hundred seventy-three professionals completed the survey 177 physicians (47%), 51 nurses (14%), 21 pharmacists (6%), 31 laboratory technicians (8%), and 88 others (24%); 5 (1%) participants had missing professional information. The average teamwork climate score across all professionals in the study was 70.5 (SD = 24.2). Pharmacists rated the teamwork climate the lowest, with a mean score of 63.9 (SD = 29.5); nurses and laboratory technicians rated teamwork higher, with means of 74.5 (SD = 21.7) and 74.2 (SD = 27.1), respectively; and physicians rated teamwork 66.0 (SD = 23.6). Collaboration with other health care providers was reported as poorer by physicians compared with nurses and pharmacists. CONCLUSION Although overall teamwork scores were consistent with ambulatory studies in the United States, important subgroup variations provide targets for intervention. Physicians rated collaboration as poor both intra- and interprofessionally. Pharmacists rated interprofessional teamwork with nurses as poor. Efforts to transform cancer care must focus on building trust among the key stakeholders. This is critical in low-resource settings, which must maximize the use of limited resources to improve patient outcomes.Due to the structural constraints of wheelchairs for users with motor disabilities, it is essential to understand and ensure their proper functioning for the quality of life of these users. https://www.selleckchem.com/products/ly333531.html The main objective of this study is to analyze the stresses and displacements in a wheelchair using the finite element method to evaluate its functional and structural aspects though simulations. Influenced by normative techniques that consider ergonomic, anthropometric and biomechanical, factors were considered to verify the compliance of this equipment considering current standards. Results were compared with experimental analyses performed by the Brazilian National Institute of Metrology, Quality and Technology (INMETRO). Results showed that von Mises stress limit values were exceeded in the chair frame by 6.5%, in the collision analysis by 72.1%, and in the footrest by 189.4%. This indicated that the structure of the analyzed wheelchair is not adequated based on simulation results, same as INMETRO reports.Background Occupational therapy-based interventions may help people with advanced cancer to live actively despite their illness. However, there is limited evidence concerning what kinds of content intervention should encompass, and how this should be done.Objective To describe the development and content of an occupational therapy-based intervention programme for people with advanced cancer living at home.Material and methods In the development of the intervention, an evidence synthesis was performed based on a systematic literature search, data from a cross-sectional study, and experiences from an expert panel.Results The programme contains six components 1) An initial interview to select which of the other five components to address, based on the participants' individual needs. The interview addressed problems and needs of participants in relation to prioritized activities, in order to tailor the following components 2) prioritisation of resources, energy and everyday activities; 3) adaptation of activities; 4) adaptation of posture and seating; 5) provision of assistive technology; and, 6) modification of the physical home environment.
annualreviews.org/page/journal/pubdates for revised estimates.Purpose To study the complication rate of NdYAG laser posterior capsulotomy in patients with uveitis.Method Retrospective case note analysis of pseudophakic uveitis patients having undergone NdYAG laser posterior capsulotomy between January 2016 and December 2018. Complications documented included uveitis flare, raised intraocular pressure, intraocular lens damage/displacement, cystoid macular edema, and retinal detachment.Results There were 39 eyes of 38 patients (20M, 18F; age 27-89 years). Mean interval between cataract surgery and laser was 55 months (range 8-286 months). Mean laser energy was 79 mJ (range 33-207 mJ). At 3 months 62% of eyes achieved a 2-5 Snellen line improvement that was maintained at 12 months. Vision was unchanged in 21% of eyes due to preexisting pathology, with no eyes having worse vision. No post-laser complications were documented.Conclusions NdYAG laser posterior capsulotomy is a safe procedure in uveitis patients, resulting in a good improvement in vision.Background Lung cancer is the leading cause of cancer-related death worldwide, imposing an enormous economic burden on society. Several studies have identified a link between the genetic polymorphisms in vitamin D pathways and lung cancer risk; however, the results remain inconclusive. The aim of this study was to estimate the effect of polymorphisms in the vitamin D receptor (VDR) and GC genes on lung cancer risk. Methods Eligible case-control studies published between January 2000 and December 2018 were searched and studied. The pooled odds ratio and its 95% confidence interval were used to estimate the effect. Results Fifteen articles that included 4732 lung cancer patients and 4337 controls were identified for this study. Our results demonstrated that the VDR Bsm1 polymorphism (p less then 0.05) and the TC and TT+TC genotypes of the Cdx2 polymorphism (p less then 0.05) were protective factors for avoiding lung cancer incidence, while T allele and TT genotype of Taq1 polymorphism (p less then 0.05) wpulations. Future case-control studies with different ethnicities are still needed to generalize these associations.PURPOSE There are strategies to bring quality cancer care to underserved patients, but poor use of the principles of teamwork is a major barrier to achieving quality services. The intent of this study was to assess teamwork as perceived by health care workers caring for patients with cancer. METHODS We conducted a survey among health care professionals in cancer care at 3 tertiary centers in southwestern Nigeria from July to November 2016. Respondents rated teamwork using the Safety Attitudes Questionnaire; we focused on the teamwork climate subscale comparing health care providers and institutions using analysis of variance and on collaboration using logistic regression. RESULTS Three hundred seventy-three professionals completed the survey 177 physicians (47%), 51 nurses (14%), 21 pharmacists (6%), 31 laboratory technicians (8%), and 88 others (24%); 5 (1%) participants had missing professional information. The average teamwork climate score across all professionals in the study was 70.5 (SD = 24.2). Pharmacists rated the teamwork climate the lowest, with a mean score of 63.9 (SD = 29.5); nurses and laboratory technicians rated teamwork higher, with means of 74.5 (SD = 21.7) and 74.2 (SD = 27.1), respectively; and physicians rated teamwork 66.0 (SD = 23.6). Collaboration with other health care providers was reported as poorer by physicians compared with nurses and pharmacists. CONCLUSION Although overall teamwork scores were consistent with ambulatory studies in the United States, important subgroup variations provide targets for intervention. Physicians rated collaboration as poor both intra- and interprofessionally. Pharmacists rated interprofessional teamwork with nurses as poor. Efforts to transform cancer care must focus on building trust among the key stakeholders. This is critical in low-resource settings, which must maximize the use of limited resources to improve patient outcomes.Due to the structural constraints of wheelchairs for users with motor disabilities, it is essential to understand and ensure their proper functioning for the quality of life of these users. https://www.selleckchem.com/products/ly333531.html The main objective of this study is to analyze the stresses and displacements in a wheelchair using the finite element method to evaluate its functional and structural aspects though simulations. Influenced by normative techniques that consider ergonomic, anthropometric and biomechanical, factors were considered to verify the compliance of this equipment considering current standards. Results were compared with experimental analyses performed by the Brazilian National Institute of Metrology, Quality and Technology (INMETRO). Results showed that von Mises stress limit values were exceeded in the chair frame by 6.5%, in the collision analysis by 72.1%, and in the footrest by 189.4%. This indicated that the structure of the analyzed wheelchair is not adequated based on simulation results, same as INMETRO reports.Background Occupational therapy-based interventions may help people with advanced cancer to live actively despite their illness. However, there is limited evidence concerning what kinds of content intervention should encompass, and how this should be done.Objective To describe the development and content of an occupational therapy-based intervention programme for people with advanced cancer living at home.Material and methods In the development of the intervention, an evidence synthesis was performed based on a systematic literature search, data from a cross-sectional study, and experiences from an expert panel.Results The programme contains six components 1) An initial interview to select which of the other five components to address, based on the participants' individual needs. The interview addressed problems and needs of participants in relation to prioritized activities, in order to tailor the following components 2) prioritisation of resources, energy and everyday activities; 3) adaptation of activities; 4) adaptation of posture and seating; 5) provision of assistive technology; and, 6) modification of the physical home environment.
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